Publication Name	World Journal of Radiology
Manuscript ID	125365
DOI	10.4329/wjr.125365
Country	China

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Case Report
Article Title	Amiodarone-induced liver injury with bright liver sign: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Zheng-Qing Shen, Xiao-Xiao Xia, Die-Wen Dong, Xian-Feng Zhang and Nan-Jing Shi
Funding Agency and Grant Number	Funding Agency Grant Number The Construction Fund of Key Medical Disciplines of Hangzhou, Clinical Research and Evaluation 2025HZGF04
Corresponding Author	Nan-Jing Shi, Department of Endocrinology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, No. 261 Huansha Road, Hangzhou 310006, Zhejiang Province, China. 21618295@zju.edu.cn
Key Words	Amiodarone; Hepatic iodine deposition; Drug-induced liver injury; Computed tomography; Magnetic resonance imaging; Hemochromatosis; Case report
Core Tip	We report a case of amiodarone-induced hepatic iodine deposition and review the relevant literature to highlight the key distinguishing features between amiodarone-induced liver injury (AILI) and hemochromatosis. Although diffuse hepatic hyperattenuation on computed tomography can be easily misdiagnosed as hemochromatosis, a normal T2-weighted imaging (T2WI) signal on magnetic resonance imaging, in contrast to the diffuse hypointensity across all sequences typically observed in hemochromatosis, may aid in differential diagnosis. However, mildly decreased hepatic signal intensity on T2WI does not definitively exclude AILI. Normal serum iron parameters further support an accurate differential diagnosis.
Citation	Shen ZQ, Xia XX, Dong DW, Zhang XF, Shi NJ. Amiodarone-induced liver injury with bright liver sign: A case report. World J Radiol 2026; In press DOI: https://doi.org/10.4329/wjr.125365
PDF	125365-in-press.pdf

Received	2026-07-08 03:12
Peer-Review Started	2026-07-08 03:12
First Decision by Editorial Office Director
Return for Revision	2026-08-03 03:21
Revised	2026-08-12 14:12
Publication Fee Transferred	2026-08-21 08:44
Second Decision by Editor	2026-09-20 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-09-20 10:51
Articles in Press	2026-09-20 10:51
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8470 (online)
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