Publication Name	World Journal of Cardiology
Manuscript ID	125738
DOI	10.4330/wjc.125738
Country	Russia

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Retrospective Cohort Study
Article Title	Factors associated with one-year mortality in patients with hyponatremia hospitalized in a cardiology department: An exploratory retrospective cohort study
Manuscript Source	Invited Manuscript
All Author List	Kristina G Pereverzeva, Sergey S Yakushin, Yulia O Cherkasova, Tatiana A Korchagina and Dmitry A Kuznetsov
Funding Agency and Grant Number
Corresponding Author	Sergey S Yakushin, Professor, Department of Hospital Therapy with a Course in Medical and Social Expertise, Federal State Budgetary Educational Institution of Higher Education I.P. Pavlov Ryazan State Medical University of the Ministry of Health of the Russian Federation, No. 96 Stroykova Street, Ryazan 390026, Ryazanskaya Oblast’, Russia. s.yakushin@rzgmu.ru
Key Words	Hyponatremia; Chronic heart failure; Creatine kinase-MB; One-year mortality; Cox regression; Retrospective cohort study
Core Tip	Hyponatremia in cardiac inpatients is associated with high one-year mortality (44.5%). In this exploratory analysis, factors associated with one-year mortality included stage II chronic heart failure, lower minimum sodium, and elevated creatine kinase-MB activity. However, the association with minimum sodium was not confirmed in sensitivity analyses, whereas creatine kinase-MB and stage II chronic heart failure remained significant in the Firth’s penalized model. These findings are hypothesis-generating and require prospective validation.
Citation	Pereverzeva KG, Yakushin SS, Cherkasova YO, Korchagina TA, Kuznetsov DA. Factors associated with one-year mortality in patients with hyponatremia hospitalized in a cardiology department: An exploratory retrospective cohort study. World J Cardiol 2026; In press DOI: https://doi.org/10.4330/wjc.125738
PDF	125738-in-press.pdf

Received	2026-07-17 07:03
Peer-Review Started	2026-07-17 07:04
First Decision by Editorial Office Director
Return for Revision	2026-09-01 12:08
Revised	2026-09-13 03:55
Publication Fee Transferred
Second Decision by Editor	2026-11-02 02:18
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-11-02 02:41
Articles in Press	2026-11-02 02:41
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8462 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com