Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	125816
Country	India

Category	Oncology
Manuscript Type	Minireviews
Article Title	Sarcopenia in gastrointestinal malignancies: Assessment, prognostic significance, and multidisciplinary management
Manuscript Source	Invited Manuscript
All Author List	Aishwarya Venugopalan and Prashant Sirohiya
Funding Agency and Grant Number
Corresponding Author	Prashant Sirohiya, Assistant Professor, Department of Onco-Anaesthesia and Palliative Medicine, National Cancer Institute (Jhajjar), All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi 110029, Delhi, India. prashantsirohiya@aiims.edu
Key Words	Sarcopenia; Cancer cachexia; Gastrointestinal neoplasms; Body composition; Prognosis; Multidisciplinary management
Core Tip	Sarcopenia is common in gastrointestinal cancers and independently predicts postoperative complications, treatment toxicity, reduced immunotherapy efficacy and poor survival. Opportunistic computed tomography analysis of skeletal muscle at the third lumbar vertebra allows practical, low-cost detection using imaging already performed for staging. Because its causes are multifactorial, effective management combines nutritional optimization, resistance and aerobic exercise, surgical prehabilitation and, in selected patients, pharmacotherapy such as anamorelin. Embedding routine muscle assessment and multimodal, multidisciplinary intervention into cancer care may improve outcomes in this vulnerable population.
Citation	Venugopalan A, Sirohiya P. Sarcopenia in gastrointestinal malignancies: Assessment, prognostic significance, and multidisciplinary management. World J Gastrointest Oncol 2026; In press

Received	2026-07-17 07:03
Peer-Review Started	2026-07-17 07:03
First Decision by Editorial Office Director
Return for Revision	2026-07-25 08:40
Revised	2026-08-08 16:55
Publication Fee Transferred
Second Decision by Editor	2026-10-23 02:59
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-10-23 09:16
Articles in Press	2026-10-23 09:16
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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