Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	126020
DOI	10.4240/wjgs.126020
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Development and validation of a psoas muscle thickness-based prediction model for hepatic encephalopathy after transjugular intrahepatic portosystemic shunt
Manuscript Source	Unsolicited Manuscript
All Author List	Li Dong, Jing-Qiu Zhang, Zhi-Yang Chen, Jin-Chang Xiao, Shi-Jiang Tian, Xin-Jian Xu, Chang-Long Hou, Yao Zheng, Yong-Hui Zhang, Pin Chen, Hao Xu, XiangZhong Huang, Chun-Ze Zhou and De-Lei Cheng
Funding Agency and Grant Number	Funding Agency Grant Number the Research Project of Anhui Provincial Health Committee AHwj2023a20508
Corresponding Author	De-Lei Cheng, MD, Department of Interventional Radiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine University of Science and Technology of China, No.17 Lujiang Road, Hefei 230000, Anhui Province, China. chengdelei@ustc.edu.cn
Key Words	Transjugular intrahepatic portosystemic shunt; Overt hepatic encephalopathy; Psoas muscle thickness-to-height ratio; Prediction model; Cirrhosis; Hepatitis B
Core Tip	We developed and validated a prediction model incorporating an objective marker of nutritional reserve to estimate 12-month risk of overt hepatic encephalopathy (OHE) after initial transjugular intrahepatic portosystemic shunt (TIPS) placement in patients without prior OHE. The simplified age–bilirubin–creatinine–psoas muscle thickness (APTC) score (range 5-14 points) showed higher discrimination than the Model for End-Stage Liver Disease, Child-Pugh, Freiburg Index of Post-TIPS Survival, and, in an exploratory comparison, Modified TIPS Score. Using routine preprocedural imaging and laboratory data, APTC may support risk communication and closer monitoring in this primary-prevention population. However, it remains unvalidated in patients with previous OHE and should not, by itself, trigger prophylaxis.
Citation	Dong L, Zhang JQ, Chen ZY, Xiao JC, Tian SJ, Xu XJ, Hou CL, Zheng Y, Zhang YH, Pin Chen, Xu H, Huang XZ, Zhou CZ, Cheng DL. Development and validation of a psoas muscle thickness-based prediction model for hepatic encephalopathy after transjugular intrahepatic portosystemic shunt. World J Gastrointest Surg 2026; In press DOI: https://doi.org/10.4240/wjgs.126020
PDF	126020-in-press.pdf

Received	2026-07-23 09:13
Peer-Review Started	2026-07-23 09:15
First Decision by Editorial Office Director
Return for Revision	2026-08-12 01:14
Revised	2026-09-04 07:03
Publication Fee Transferred	2026-09-23 10:22
Second Decision by Editor	2026-11-02 02:19
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-11-04 10:42
Articles in Press	2026-11-04 10:42
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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