Publication Name	World Journal of Radiology
Manuscript ID	126066
DOI	10.4329/wjr.126066
Country	Japan

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Retrospective Study
Article Title	Computed tomography-guided splanchnic nerve neurolysis outcomes by tumor site in unresectable pancreatic cancer: A single-center retrospective cohort study
Manuscript Source	Unsolicited Manuscript
All Author List	Hiroshi Baba, Hajime Takaki, Yasunari Yamada, Tomoko Nakayama, Kentaro Iwaki, Kengo Fukuzawa, Mitsuteru Motomura and Yoshiki Asayama
Funding Agency and Grant Number
Corresponding Author	Hiroshi Baba, MD, Department of Radiology, Japan Community Health Care Organization Nankai Medical Center, 7-8 Tokiwanishimachi, Saiki, Oita 876-0857, Japan, Oita 876-0857, Japan. babahiroshi@oita-u.ac.jp
Key Words	Neurolytic splanchnic nerve block; Pancreatic cancer; Computed tomography-guided intervention; Cancer pain; Tumor location; Retrospective studies
Core Tip	This retrospective study evaluated outcomes after the initial computed tomography-guided neurolytic splanchnic nerve block in 22 patients with unresectable pancreatic cancer. Clinical success was achieved in 81.8%, with responses observed in both pancreatic head and body/tail tumors. No grade ≥ 3 adverse events were observed. These encouraging findings support further investigation of this approach for pancreatic cancer pain management. Larger prospective studies with standardized outcome assessments are needed to confirm the findings and clarify potential differences by tumor site.
Citation	Baba H, Takaki H, Yamada Y, Nakayama T, Iwaki K, Fukuzawa K, Motomura M, Asayama Y. Computed tomography-guided splanchnic nerve neurolysis outcomes by tumor site in unresectable pancreatic cancer: A single-center retrospective cohort study. World J Radiol 2026; In press DOI: https://doi.org/10.4329/wjr.126066
PDF	126066-in-press.pdf

Received	2026-08-07 02:59
Peer-Review Started	2026-08-07 02:59
First Decision by Editorial Office Director
Return for Revision	2026-09-04 02:45
Revised	2026-09-16 04:03
Publication Fee Transferred	2026-09-30 07:32
Second Decision by Editor	2026-10-21 02:57
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-10-21 10:10
Articles in Press	2026-10-21 10:10
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8470 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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