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Publication Name World Journal of Nephrology
Manuscript ID 126514
Country Egypt
Category Urology & Nephrology
Manuscript Type Opinion Review
Article Title From reactive to predictive nephrology: A framework for precision kidney care
Manuscript Source Invited Manuscript
All Author List Kirolos Eskandar
Funding Agency and Grant Number
Corresponding Author Kirolos Eskandar, MD, Researcher, Medicine and Surgery, Helwan University, Faculty of Medicine and Surgery, 10 Elaysmeen St. Faisel. Giza, Faisel 12511, Al Jīzah, Egypt. kiroloss.eskandar@gmail.com
Key Words Predictive nephrology; Kidney biomarkers; Artificial intelligence; Multi-omics; Digital health
Core Tip Kidney care increasingly requires approaches that complement established diagnostic and prognostic measures with information about biological injury, individualized risk, and evolving disease trajectories. Advances in biomarkers, multi-omics, artificial intelligence, and digital health offer potential opportunities, although their clinical value and readiness for routine use differ substantially. This opinion review proposes the predictive nephrology continuum, a six-stage conceptual framework linking detection, risk prediction, treatment personalization, prevention, monitoring, and adaptive management through an iterative feedback process. Its central contribution is the integration of these activities into a kidney-specific approach to clinical decision-making. Predictive nephrology should complement established evidence-based care and clinical judgment, with its ultimate value determined by demonstrated improvements in patient outcomes rather than predictive accuracy alone.
Citation Eskandar K. From reactive to predictive nephrology: A framework for precision kidney care. World J Nephrol 2026; In press
Received
2026-08-06 02:12
Peer-Review Started
2026-08-06 02:12
First Decision by Editorial Office Director
Return for Revision
2026-10-16 06:03
Revised
2026-10-16 10:24
Publication Fee Transferred
Second Decision by Editor
2026-11-09 06:24
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-11-09 11:22
Articles in Press
2026-11-09 11:22
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-6124 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com