Publication Name	World Journal of Clinical Cases
Manuscript ID	126756
DOI	10.12998/wjcc.126756
Country	Morocco

Category	Emergency Medicine
Manuscript Type	Case Report
Article Title	Priapism as a rare adverse effect of levomepromazine: A case report
Manuscript Source	Invited Manuscript
All Author List	Mohammed Taloubi, Ait Sayad Lamya and Ghizlane El Aidouni
Funding Agency and Grant Number
Corresponding Author	Mohammed Taloubi, MD, Department of Anesthesiology and Critical Care, Mohammed VI University Hospital Center, Rue El Aounia Lot El Ouiam Rue D1 NR 12, Oujda 60010, Morocco. taloubi.mohammed.16@gmail.com
Key Words	Priapism; Levomepromazine; Antipsychotics; Ischemia; Phenothiazines; Case report
Core Tip	Levomepromazine-associated priapism is rarely reported despite the drug’s substantial α1-adrenergic antagonistic activity. This case is notable for the development of severe ischemic priapism only 48 hours after initiation of levomepromazine monotherapy at a therapeutic dose, with complete absence of penile pain despite profound cavernosal hypoxia and acidosis. Failure of intracavernosal phenylephrine ultimately required surgical shunting. This observation emphasizes that absence of pain does not exclude severe ischemia and that persistent erections during antipsychotic therapy require prompt evaluation and treatment to prevent irreversible cavernosal injury.
Citation	Taloubi M, Ait Sayad L, El Aidouni G Priapism as a rare adverse effect of levomepromazine: A case report. World J Clin Cases 2026; In press DOI: https://doi.org/10.12998/wjcc.126756
PDF	126756-in-press.pdf

Received	2026-08-21 07:35
Peer-Review Started	2026-08-21 07:35
First Decision by Editorial Office Director
Return for Revision	2026-09-21 00:53
Revised	2026-09-29 23:26
Publication Fee Transferred
Second Decision by Editor	2026-10-12 03:05
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-10-12 10:10
Articles in Press	2026-10-12 10:10
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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