Publication Name	World Journal of Clinical Oncology
Manuscript ID	127502
DOI	10.5306/wjco.127502
Country	Canada

Category	Oncology
Manuscript Type	Retrospective Cohort Study
Article Title	Outcomes of cytoreductive surgery for octogenarian patients with high-grade serous ovarian cancer: A Single-center experience
Manuscript Source	Invited Manuscript
All Author List	Samantha Taylor, Gabriel Levin, Lucy Gilbert, Xing Zeng, Shuk On Annie Leung, Laurence Bernard and Reitan Ribeiro
Funding Agency and Grant Number
Corresponding Author	Gabriel Levin, Division of Gynecologic Oncology, McGill University Health Centre, Montreal H4A 0B1, Quebec, Canada. gabriel.levin2@mail.mcgill.ca
Key Words	Ovarian cancer; Elderly; Cytoreduction; Octogenarians; Surgery
Core Tip	Among 42 women aged ≥ 80 years with high-grade serous ovarian cancer, most had substantial comorbidity and advanced-stage disease. Primary cytoreductive surgery (PCS) was performed in 66.7%, with complete macroscopic cytoreduction achieved in 64.3%. Despite postoperative complications in 35.7%, median progression-free and overall survival were 25 and 37 months, respectively. PCS and better Eastern Cooperative Oncology Group performance status were independently associated with improved survival. These findings suggest that carefully selected octogenarians can achieve meaningful outcomes and that treatment decisions should prioritize functional status and comorbidity burden over chronological age alone.
Citation	Taylor S, Levin G, Gilbert L, Zeng X, Leung SOA, Bernard L, Ribeiro R. Outcomes of cytoreductive surgery for octogenarian patients with high-grade serous ovarian cancer: A Single-center experience. World J Clin Oncol 2026; In press DOI: https://doi.org/10.5306/wjco.127502
PDF	127502-in-press.pdf

Received	2026-09-01 02:18
Peer-Review Started	2026-09-01 02:19
First Decision by Editorial Office Director
Return for Revision	2026-09-14 07:51
Revised	2026-09-14 14:56
Publication Fee Transferred
Second Decision by Editor	2026-11-06 06:09
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-11-06 10:31
Articles in Press	2026-11-06 10:31
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
Open Access	Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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