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Articles in Press
11/13/2026 10:29:21 AM | Browse: 38 | Download: 7
| Category |
Research & Experimental Medicine |
| Manuscript Type |
Minireviews |
| Article Title |
Stem cell preconditioning for enhanced therapeutic efficacy: Translational challenges and strategic solutions
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Han-Kun Su, Can Cui, Zhou Yu and Ke-Rui Huang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Central South University Innovation and Entrepreneurship Training Program |
D202603291914474115 |
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| Corresponding Author |
Han-Kun Su, MD, Senior Researcher, Department of Reproductive Medicine, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha 420083, Hunan Province, China. hankunsu@csu.edu.cn |
| Key Words |
Stem cell preconditioning; Stem/stromal cell therapy; Extracellular vesicles; Clinical translation; Good manufacturing practice; Critical quality attributes; Potency assays |
| Core Tip |
Stem cell preconditioning should be developed as a controlled manufacturing step within a product lifecycle framework. This review integrates product definition, mechanism of action, critical quality attributes, process standardization, potency assessment, and large-scale manufacturing. We call for a shift in attention from preconditioning stem cells’ biological enhancement alone toward reproducible product quality and interpretable clinical evidence. |
| Citation |
Su HK, Cui C, Yu Z, Huang KR. Stem cell preconditioning for enhanced therapeutic efficacy: Translational challenges and strategic solutions. World J Stem Cells 2026; In press
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| PDF |
127968-in-press.pdf
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Received |
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2026-09-14 09:05 |
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Peer-Review Started |
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2026-09-14 09:05 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-10-12 08:15 |
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Revised |
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2026-10-22 12:45 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-11-13 02:53 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-11-13 10:29 |
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Articles in Press |
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2026-11-13 10:29 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
