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Publication Name World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID 128040
DOI 10.4292/wjgpt.128040
Country Brazil
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Myths and facts about diet in metabolic dysfunction-associated steatotic liver disease—part II: Nutrition during incretin-based therapy
Manuscript Source Invited Manuscript
All Author List Sabrina Alves Fernandes and João Marcello Araujo-Neto
Funding Agency and Grant Number
Corresponding Author Sabrina Alves Fernandes, Hepatology, Santa Casa de Porto Alegre Hospital Complex, Professor Annes Dias, 295, Porto Alegre 90020-090, Rio Grande do Sul, Brazil. sabrinaafernandes@gmail.com
Key Words Metabolic dysfunction-associated steatotic liver disease; Incretins; Glucagon-like peptide-1 receptor agonists; Nutrition therapy; Sarcopenia; Weight loss; Dietary counseling
Core Tip Incretin-based therapies are changing the management of metabolic dysfunction-associated steatotic liver disease, but their appetite-suppressing effect does not make nutritional care optional. Withdrawal trials show that weight and cardiometabolic benefits are not maintained after discontinuation, and that lifestyle intervention alone does not replace the drug's effect. This review proposes 11 literature-informed, risk-stratified practical recommendations (not formal guidelines) covering nutritional and body-composition assessment, individualized protein intake with progressive resistance training, micronutrient and bone monitoring, and dietary management of gastrointestinal adverse events, and argues that nutritional follow-up should be part of incretin-based care from the start of treatment.
Citation Fernandes SA, Araujo-Neto JM. Myths and facts about diet in metabolic dysfunction-associated steatotic liver disease—part II: Nutrition during incretin-based therapy. World J Gastrointest Pharmacol Ther 2026; In press
PDF 128040-in-press.pdf
Received
2026-09-14 09:17
Peer-Review Started
2026-09-14 09:17
First Decision by Editorial Office Director
Return for Revision
2026-09-23 14:09
Revised
2026-10-07 23:25
Publication Fee Transferred
Second Decision by Editor
2026-11-09 06:09
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-11-09 11:30
Articles in Press
2026-11-09 11:30
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2150-5349 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com