Publication Name	World Journal of Clinical Cases
Manuscript ID	128515
DOI	10.12998/wjcc.128515
Country	Spain

Category	Pathology
Manuscript Type	Case Report
Article Title	Group 3 malignant proliferating trichilemmal tumor of the scalp: A case report
Manuscript Source	Invited Manuscript
All Author List	María Victoria Vieiro Medina, Laura Alonso Murillo, Marta Reguera Sanchez-Vera, Daniel Cuenca Leal, Álvaro Trascasa Caño and Santos F Jiménez de los Galanes
Funding Agency and Grant Number
Corresponding Author	María Victoria Vieiro Medina, MD, Department of General and Digestive Surgery, Hospital Universitario Infanta Elena, Av. de los Reyes Católicos, 21, Valdemoro 28342, Madrid, Spain. vickyvieiro@gmail.com
Key Words	Scalp; Hair follicle; Skin neoplasms; Neoplasm recurrence, local; Radiotherapy, adjuvant; Malignant proliferating trichilemmal tumor; Case report
Core Tip	Malignant proliferating trichilemmal tumor (MPTT) is a rare cutaneous adnexal neoplasm often misdiagnosed clinically as a benign cyst, as occurred in this case. We report a 58-year-old woman with a rapidly enlarging scalp mass, histologically classified as Group 3 (high-grade) MPTT according to the Ye et al criteria, managed with wide surgical re-excision and adjuvant radiotherapy (50 Gy in 12 fractions), with no recurrence at 6 months after the end of radiotherapy. This case shows that a long-standing, stable scalp cyst that enlarges rapidly should be excised intact and examined histologically, illustrates that a Group 3 tumor can be diagnosed even when invasion is limited and the specimen is fragmented, and, given the short follow-up, underscores the need for long-term surveillance.
Citation	Vieiro Medina MV, Alonso Murillo L, Reguera Sanchez-Vera M, Cuenca Leal D, Trascasa Caño Á, Jiménez de los Galanes SF. Group 3 malignant proliferating trichilemmal tumor of the scalp: A case report. World J Clin Cases 2026; In press DOI: https://doi.org/10.12998/wjcc.128515
PDF	128515-in-press.pdf

Received	2026-09-24 03:04
Peer-Review Started	2026-09-24 03:05
First Decision by Editorial Office Director
Return for Revision	2026-10-12 01:33
Revised	2026-10-16 13:48
Publication Fee Transferred
Second Decision by Editor	2026-10-22 03:01
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-10-22 09:05
Articles in Press	2026-10-22 09:05
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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