BPG is committed to discovery and dissemination of knowledge
Articles in Press
11/17/2023 8:44:11 AM | Browse: 22 | Download: 3
Publication Name World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID 88566
Country/Territory United States
Category Gastroenterology & Hepatology
Manuscript Type Case Control Study
Article Title Effectiveness of an amino acid beverage formulation in diarrhea-predominant irritable bowel syndrome: A pragmatic real-world study
Manuscript Source Unsolicited Manuscript
All Author List Samantha E Niles, Phil Blazy, Samuel N Cheuvront, Robert W Kenefick, Sadasivan Vidyasagar, Adam B Smith, Neil Fawkes and William Denman
Funding Agency and Grant Number
Corresponding Author Samantha E Niles, BSc, MS, Researcher, Department of Research and Development, Entrinsic Bioscience, 500 River Ridge Dr. 100, Norwood, MA 02062, United States. sniles@entrinsic.com
Key Words Diarrhea-predominant irritable bowel syndrome; Amino acid beverage formulation; Pragmatic real-world study; Medical food; Bristol Stool Form Scale; Irritable Bowel Syndrome – Severity Scoring System
Core Tip Amino-acid based medical foods have been shown to alleviate symptoms of drug induced gastrointestinal side effects, especially diarrhea severity. Diarrhea predominant irritable bowel syndrome (IBS-D) is a chronic gastrointestinal disorder that affects up to 9% of people worldwide. In this pragmatic, real-world study, an amino acid beverage was demonstrated to be tolerable and efficacious when used as an adjunct to standard of care for adults with IBS-D. Participants demonstrated improvements in both overall irritable bowel syndrome symptom severity and IBS-D symptoms within just two weeks. These results suggest that this amino acid-based beverage can be safely integrated into IBS-D standard of care for symptom improvement.
Citation Niles SE, Blazy P, Cheuvront SN, Kenefick RW, Vidyasagar S, Smith AB, Fawkes N, Denman W. Effectiveness of an amino acid beverage formulation in diarrhea-predominant irritable bowel syndrome: A pragmatic real-world study. World J Gastrointest Pharmacol Ther 2023; In press
2023-09-29 14:03
Peer-Review Started
2023-09-29 14:03
To Make the First Decision
Return for Revision
2023-10-10 19:17
2023-10-16 15:14
Second Decision
2023-11-10 04:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-11-17 08:44
Articles in Press
2023-11-17 08:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2150-5349 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Cong Lin
Reviewer Code 04451514, 06730456, 02536349, 00068348, 06730456, and 02536349
Editorial Director
Journal Chief Editor
Company Chief Editor Jin-Lei Wang
Language Editor
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma