Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Cohort Study |
Article Title |
Clinical profile and outcomes of hepatocellular carcinoma in primary Budd-Chiari syndrome
|
Manuscript Source |
Invited Manuscript |
All Author List |
Ankit Agarwal, Sagnik Biswas, Shekhar Swaroop, Arnav Aggarwal, Ayush Agarwal, Gautam Jain, Anshuman Elhence, Arun Vaidya, Amit Gupte, Ravi Mohanka, Ramesh Kumar, Ashwani Kumar Mishra, Shivanand Gamanagatti, Shashi Bala Paul, Subrat Kumar Acharya, Akash Shukla and Shalimar |
Funding Agency and Grant Number |
|
Corresponding Author |
Shalimar, MD, Professor, Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Sri Aurobindo Marg, New Delhi 110029, Delhi, India. drshalimar@yahoo.com |
Key Words |
Hepatocellular carcinoma; Budd chiari syndrome; Trans arterial chemoembolisation; Hepatic venous outflow tract obstruction |
Core Tip |
Hepatocellular carcinoma is not uncommon in patients with Budd Chiari syndrome. It may be the presenting feature or may develop later during illness. Early diagnosis and intervention are the key to improving outcomes. Strategies for surveillance include serial alpha fetoprotein and ultrasound assessment every 6 months with biopsy in cases with high clinical suspicion. Endovascular intervention is usually done prior to therapy for hepatocellular carcinoma which improves liver functions. Liver transplantation and surgical resection have curative potential while loco regional therapy may be offered to a select group with more advanced disease which improves outcomes in these patients. |
Citation |
Agarwal A, Biswas S, Swaroop S, Aggarwal A, Agarwal A, Jain G, Elhence A, Vaidya A, Gupte A, Mohanka R, Kumar R, Mishra AK, Gamanagatti S, Paul SB, Acharya SK, Shukla A, Shalimar. Clinical profile and outcomes of hepatocellular carcinoma in primary Budd-Chiari syndrome. World J Gastrointest Oncol 2024; 16(3): 699-715 |