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Articles in Press
11/17/2023 8:43:13 AM | Browse: 24 | Download: 6
Publication Name |
World Journal of Radiology |
Manuscript ID |
88642 |
Country/Territory |
Japan |
Category |
Radiology, Nuclear Medicine & Medical Imaging |
Manuscript Type |
Basic Study |
Article Title |
Imaging assessment of photosensitizer emission induced by radionuclide-derived Cherenkov radiation using charge-coupled device optical imaging and long-pass filters
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Winn Aung, Atsushi B Tsuji, Kazuaki Rikiyama, Fumihiko Nishikido, Satoshi Obara and Tatsuya Higashi |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Grant-in-Aid for Scientific Research (C) from the Japan Society for the Promotion of Science |
21K07740 |
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Corresponding Author |
Winn Aung, MBBS, PhD, Senior Researcher, Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan. winn.aung@qst.go.jp |
Key Words |
Tetrakis (4-carboxyphenyl) porphyrin; Photosensitizer emission; Radionuclide; Cherenkov radiation; Optical imaging; Long-pass filters |
Core Tip |
Radionuclides produce Cherenkov radiation (CR), which can potentially activate photosensitizers (PSs) in phototherapy. However, a cost-effective method to determine whether radionuclide-derived CR excites PSs and the measurement of fluorescence emitted by excited PS remain elusive. We propose a cost-effective method using a charge-coupled device optical imaging system combined with long-pass filters and subtraction image processing to distinguish CR and PS fluorescence emission. As a proof-of-concept, 64CuCl2 and the PS tetrakis (4-carboxyphenyl) porphyrin were used in the experiments. This method can contribute to accelerating the development of Cherenkov energy transfer imaging and the discovery of new PSs. |
Citation |
Aung W, Tsuji AB, Rikiyama K, Nishikido F, Obara S, Higashi T. Imaging assessment of photosensitizer emission induced by radionuclide-derived Cherenkov radiation using charge-coupled device optical imaging and long-pass filters. World J Radiol 2023; 15(11): 315-323 |
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Received |
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2023-10-03 14:33 |
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Peer-Review Started |
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2023-10-03 14:34 |
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To Make the First Decision |
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Return for Revision |
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2023-10-17 08:03 |
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Revised |
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2023-10-26 18:21 |
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Second Decision |
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2023-11-14 05:13 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2023-11-17 08:43 |
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Articles in Press |
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2023-11-17 08:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-11-14 01:09 |
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Typeset the Manuscript |
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2023-11-21 05:34 |
ISSN |
1949-8470 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Assistant Editor |
Assistant Editor |
Science Editor |
Cong Lin |
Reviewer Code |
02519358 |
Editorial Director |
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Journal Chief Editor |
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Company Chief Editor |
Jin-Lei Wang |
Language Editor |
Donna Fox |
Production Editor |
Si Zhao |
Responsible Production Editor |
Si Zhao |
Responsible Science Editor |
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Proofing Editorial Director |
Jin-Lei Wang |
Proofing Editor-in-Chief |
Lian-Sheng Ma |
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