Publication Name	World Journal of Clinical Cases
Manuscript ID	90710
Country	Cyprus

Category	Infectious Diseases
Manuscript Type	Editorial
Article Title	Antifungal pipeline: Is there light at the end of the tunnel?
Manuscript Source	Invited Manuscript
All Author List	Georgios Schinas, Nikolaos Spernovasilis and Karolina Akinosoglou
Funding Agency and Grant Number
Corresponding Author	Nikolaos Spernovasilis, BSc, MD, MSc, PhD, Director, Department of Infectious Diseases, German Oncology Center, Limassol 4108, Cyprus. nikspe@hotmail.com
Key Words	Antifungals; Resistance; Fosmanogepix; Ibrexafungerp; Olorofim
Core Tip	The landscape of antifungal therapy has long been dominated by a handful of drug classes, namely azoles, polyenes, and echinocandins. Issues such as the development of resistance/tolerance, interactions and inherent toxicity, and a narrow spectrum of activity have limited their therapeutic utility to clinicians. All these limitations underline the urgent need for novel approaches, with the pipeline for new antifungals having been relatively dry for about 30 years. Thankfully, the pharmaceutical landscape has recently shown promising signs of innovation regarding antifungal agents.
Citation	Schinas G, Spernovasilis N, Akinosoglou K. Antifungal pipeline: Is there light at the end of the tunnel? World J Clin Cases 2024; In press

Received	2023-12-11 20:53
Peer-Review Started	2023-12-11 20:53
To Make the First Decision
Return for Revision	2024-03-06 21:51
Revised	2024-03-19 04:20
Second Decision	2024-04-19 02:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-19 08:17
Articles in Press	2024-04-19 08:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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