Publication Name	World Journal of Gastroenterology
Manuscript ID	90756
Country	France

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Chitin-glucan improves important pathophysiological features of irritable bowel syndrome
Manuscript Source	Unsolicited Manuscript
All Author List	Caroline Valibouze, Caroline Dubuquoy, Philippe Chavatte, Michaël Genin, Veronique Maquet, Salvatore Modica, Pierre Desreumaux and Christel Rousseaux
Funding Agency and Grant Number	Funding Agency Grant Number Service Public de Wallonie (SPW-EER, convention 8588, Belgium)
Corresponding Author	Christel Rousseaux, PhD, Researcher, Intestinal Biotech Development, Faculté de Médicine, Pole Recherche Amphi JK, Bd du Pr Jules Leclercq, Lille 59045, France. crousseaux@ibd-biotech.com
Key Words	Chitin-glucan; Irritable bowel syndrome; Abdominal pain; Inflammation; Intestinal barrier; Molecular modelling; Microbial cell walls chelation
Core Tip	Currently available irritable bowel syndrome (IBS) treatments are often inadequate. Chitin-glucan is a novel, well-tolerated, non-digestible prebiotic considered a safe food ingredient by the European Food Safety Authority. This study suggests new capacities of chitin-glucan to target most pathophysiological mechanisms of IBS and its therapeutic potential as a promising new generation of prebiotics for patients with IBS or IBS-like symptoms.
Citation	Valibouze C, Dubuquoy C, Chavatte P, Genin M, Maquet V, Modica S, Desreumaux P, Rousseaux C. Chitin-glucan improves important pathophysiological features of irritable bowel syndrome. World J Gastroenterol 2024; 30(16): 2258-2271

Received	2024-01-25 21:32
Peer-Review Started	2024-01-25 21:32
To Make the First Decision
Return for Revision	2024-02-01 21:53
Revised	2024-02-21 11:59
Second Decision	2024-03-28 06:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-03-28 08:48
Articles in Press	2024-03-28 08:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-21 08:54

ISSN	1007-9327 (print) and 2219-2840 (online)
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