Publication Name	World Journal of Clinical Cases
Manuscript ID	90797
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Detection and analysis of serum bile acid profile in patients with colonic polyps
Manuscript Source	Unsolicited Manuscript
All Author List	Xin Ji and Hong Chen
Funding Agency and Grant Number
Corresponding Author	Hong Chen, Doctor, Professor, Department of Gastroenterology, Zhongda Hospital Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing 210009, Jiangsu Province, China. njchenhong66@163.com
Key Words	Serum; Bile acid profile; Colonic polyps; Bile acid metabolism
Core Tip	This study shows that the serum primary conjugated bile acid (BA) levels in the colonic polyp group were significantly higher than those in the control group (P < 0.05), while the secondary free BA, deoxycholic acid content was lower than that in the control group. Patients with various polyp sizes, locations, morphologies, and pathological types had variable serum BA profile, according to subgroup study of colonic polyps. Therefore, analyzing the changes in serum BA profile may provide new ideas for finding new targets for the treatment of colonic tumors.
Citation	Ji X, Chen H. Detection and analysis of serum bile acid profile in patients with colonic polyps. World J Clin Cases 2024; 12(13): 2160-2172

Received	2023-12-14 07:35
Peer-Review Started	2023-12-14 07:35
To Make the First Decision
Return for Revision	2024-02-13 07:53
Revised	2024-02-21 13:21
Second Decision	2024-03-28 06:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-03-28 08:24
Articles in Press	2024-03-28 08:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-17 07:01

ISSN	2307-8960 (online)
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