Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	90891
Country	France

Category	Critical Care Medicine
Manuscript Type	Letter to the Editor
Article Title	Should we perform decompressive laparotomy during severe acute pancreatitis with intra-abdominal hypertension below 25 mmHg: Only the gut knows
Manuscript Source	Unsolicited Manuscript
All Author List	Thibault Vieille, Melissa Crotet, Celia Turco, Paul Monasterolo, Hadrien Winiszewski and Gael Piton
Funding Agency and Grant Number
Corresponding Author	Thibault Vieille, MD, Doctor, Medical Intensive Care Unit, Besancon University Hospital, 3 bd Fleming, Besancon 25000, France. thibault.vieille91@gmail.com
Key Words	Acute pancreatitis; Abdominal compartment syndrome; Decompressive laparotomy; Mesenteric ischemia; Intra-abdominal pressure; Abdominal perfusion pressure
Core Tip	In a recent review, Nasa et al discussed the optimal timing for decompressive laparotomy during severe acute pancreatitis. In line with the authors, we think that practitioners should not only focus on intra-abdominal pressure (IAP) levels to consider laparotomy but should also consider the gut viability. Indeed, intra-abdominal hypertension may decrease bowel perfusion pressure and precipitate non-occlusive mesenteric ischemia even with IAP below 25 mmHg. The objective of decompressive laparotomy is to restore mesenteric blood flow and prevent from transmural necrosis from occurring.
Citation	Vieille T, Crotet M, Turco C, Monasterolo P, Winiszewski H, Piton G. Should we perform decompressive laparotomy during severe acute pancreatitis with intra-abdominal hypertension below 25 mmHg: Only the gut knows. World J Gastrointest Surg 2024; In press

Received	2023-12-16 14:54
Peer-Review Started	2023-12-16 14:54
To Make the First Decision
Return for Revision	2024-03-06 04:23
Revised	2024-03-11 16:54
Second Decision	2024-04-15 02:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-15 06:05
Articles in Press	2024-04-15 06:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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