Publication Name	World Journal of Diabetes
Manuscript ID	91056
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Minireviews
Article Title	Adipose-derived stem cells in diabetic foot care: Bridging clinical trials and practical application
Manuscript Source	Invited Manuscript
All Author List	Song-Lu Tseng, Lin Kang, Zhu-jun Li, Li-Quan Wang, Zi-Ming Li, Tian-Hao Li, Jie-Yu Xiang, Jiu-Zuo Huang, Nan-Ze Yu and Xiao Long
Funding Agency and Grant Number	Funding Agency Grant Number National Key R&D Program of China 2020YFE0201600 CAMS Innovation Fund for Medical Sciences 2020-I2M- C&T-A-004 National High Level Hospital Clinical Research Funding 2022-PUMCH-B-041 and 2022-PUMCH-A-210 National High-Level Hospital Clinical Research Funding 2022-PUMCH-C-025
Corresponding Author	Xiao Long, MD, PhD, Chief Physician, Department of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China. pumclongxiao@126.com
Key Words	Adipose-derived stem cells; Diabetic foot ulcers; Wound healing; Clinical trials; Stem cell therapy; Wound care
Core Tip	This review critically analyzes the current state of research on the efficacy of adipose-derived stem cells (ADSCs) against diabetic foot ulcers (DFUs). It offers a comprehensive overview of diabetic foot classification, clinical management, and the ADSC therapy intricacies. Despite its potential, the field faces challenges like biased trial designs, ambiguous inclusion criteria and intervention strategies. The review highlights these issues and discusses the preclinical efforts to enhance ADSC efficacy. It emphasizes the necessity of more rigorous research and refinement of therapeutic approaches to improve treatment outcomes in diabetic wound care and guide future research.
Citation	Tseng SL, Kang L, Li ZJ, Wang LQ, Li ZM, Li TH, Xiang JY, Huang JZ, Yu NZ, Long X. Adipose-derived stem cells in diabetic foot care: Bridging clinical trials and practical application. World J Diabetes 2024; In press

Received	2023-12-20 21:56
Peer-Review Started	2023-12-20 21:56
To Make the First Decision
Return for Revision	2024-02-20 01:55
Revised	2024-03-03 10:02
Second Decision	2024-04-12 02:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-19 06:54
Articles in Press	2024-04-19 06:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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