Publication Name	World Journal of Diabetes
Manuscript ID	91093
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Observational Study
Article Title	Correlation between cerebral neurotransmitters levels by proton magnetic resonance spectroscopy and HbA1c in patients with type 2 diabetes
Manuscript Source	Unsolicited Manuscript
All Author List	Xiang-Yu Gao, Chen-Xia Zhou, Hong-Mei Li, Min Cheng, Da Chen, Zi-Yi Li, Bo Feng and Jun Song
Funding Agency and Grant Number	Funding Agency Grant Number Academic Leaders Training Program of Pudong Health Bureau of Shanghai No. PWRd2023-03 Clinical Research Fund of Shanghai Municipal Commission of Health No. 202040136 National Natural Science Foundation of China No. 82070842 Jiangxi Health Commission Science and Technology Plan Project No. 202212838 and No. 202212852
Corresponding Author	Jun Song, PhD, N/A, Department of Endocrinology, East Hospital, Tongji University School of Medicine, No. 150 Jimo Road, Shanghai 200120, China. songjuntj@tongji.edu.cn
Key Words	Type 2 diabetes mellitus; Hemoglobin A1c; Proton magnetic resonance spectroscopy; Neurotransmitters; Central neuropathy
Core Tip	Diabetic neuropathy is one of the most common chronic complications, and its pathogenesis has not been fully clarified until now, especially the central neuropathy. Cognitive dysfunction is the main manifestation of central neuropathy, although cognitive impairments tend to be neglected in diabetes, there is factually increasing evidence linking diabetes mellitus (DM) to cognitive dysfunction. Several studies indicated that the changes in cerebral neurotransmitter levels are associated with a variety of neurological abnormalities. Here, we described the relationship between cerebral neurotransmitters concentrations that were measured using proton magnetic resonance spectroscopy and hemoglobin A1c levels in patients with type 2 DM.
Citation	Gao XY, Zhou CX, Li HM, Cheng M, Chen D, Li ZY, Feng B, Song J. Correlation between cerebral neurotransmitters levels by proton magnetic resonance spectroscopy and HbA1c in patients with type 2 diabetes. World J Diabetes 2024; In press

Received	2023-12-22 00:59
Peer-Review Started	2023-12-22 00:59
To Make the First Decision
Return for Revision	2024-03-06 03:47
Revised	2024-03-28 02:17
Second Decision	2024-04-17 09:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-24 06:30
Articles in Press	2024-04-24 06:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com