Publication Name	World Journal of Transplantation
Manuscript ID	91146
Country	United States

Category	Medicine, General & Internal
Manuscript Type	Editorial
Article Title	Tacrolimus-induced posterior reversible encephalopathy syndrome following liver transplantation
Manuscript Source	Invited Manuscript
All Author List	Arthur Dilibe, Lakshmi Subramanian, Tracy-Ann Poyser, Osejie Oriaifo, Ryan Brady, Sashwath Srikanth, Olanrewaju Adabale, Olayiwola Akeem Bolaji and Hassam Ali
Funding Agency and Grant Number
Corresponding Author	Hassam Ali, MD, Doctor, Division of Gastroenterology and Hepatology, East Carolina University/Brody School of Medicine, 2100 Statonsburg Road, Greenville, Greenville, NC 27858, United States. hassamali155@gmail.com
Key Words	Posterior reversible encephalopathy syndrome; Liver transplantation; Tacrolimus; Immunocompromised patients; Neurological complications; Solid organ transplant
Core Tip	Tacrolimus, a crucial immunosuppressant in liver transplantation, is associated with the rare but serious complication of posterior reversible encephalopathy syndrome (PRES). Although the incidence is relatively low (0.5%-5%) in solid organ transplant recipients, the presentation of PRES can vary significantly, including seizures and visual disturbances. This condition, primarily affecting the parietal and occipital lobes, underscores the need for diligent monitoring and early intervention in liver transplant patients undergoing Tacrolimus therapy. The case presented highlights the complexities in diagnosing and managing Tacrolimus-related PRES, emphasizing the critical balance between adequate immunosuppression and the risk of severe neurological adverse effects.
Citation	Dilibe A, Subramanian L, Poyser TA, Oriaifo O, Brady R, Srikanth S, Adabale O, Bolaji OA, Ali H. Tacrolimus-induced posterior reversible encephalopathy syndrome following liver transplantation. World J Transplant 2024; In press

Received	2023-12-23 00:22
Peer-Review Started	2023-12-23 00:22
To Make the First Decision
Return for Revision	2024-03-31 00:09
Revised	2024-04-13 22:19
Second Decision	2024-04-25 02:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-25 10:19
Articles in Press	2024-04-25 10:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3230 (online)
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