Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	91587
Country	India

Category	Endocrinology & Metabolism
Manuscript Type	Review
Article Title	Type 2 diabetes in children and adolescents: Exploring the disease heterogeneity and research gaps to optimum management
Manuscript Source	Invited Manuscript
All Author List	Subhodip Pramanik, Sunetra Mondal, Rajan Palui and Sayantan Ray
Funding Agency and Grant Number
Corresponding Author	Sayantan Ray, MBBS, MD, Assistant Professor, Department of Endocrinology, All India Institute of Medical Sciences, Sijua, Patrapada, Bhubaneswar 751019, Odisha, India. sayantan.ray30@gmail.com
Key Words	Type 2 diabetes mellitus; Children and adolescents; Pathophysiology; Heterogeneity; Complications; Treatment options; Barriers
Core Tip	The incidence and prevalence of type 2 diabetes mellitus (T2DM) in children and adolescents has dramatically increased over the past 20 years. Accumulating evidence suggest that youth-onset T2DM presents with unique characteristics, demographics and disease progression compared to adult-onset T2DM. Besides, the available therapeutic options for children and adolescents with T2DM are inadequate. T2DM in children and adolescents is becoming a public health concern worldwide. Research programs should aim to overcome the challenges seen with clinical studies in this population in order to address the unmet need of optimal management of T2DM in children and adolescents.
Citation	Pramanik S, Mondal S, Palui R, Ray S. Type 2 diabetes in children and adolescents: Exploring the disease heterogeneity and research gaps to optimum management. World J Clin Pediatr 2024; In press

Received	2023-12-31 05:30
Peer-Review Started	2023-12-31 05:31
To Make the First Decision
Return for Revision	2024-03-11 09:20
Revised	2024-04-07 06:10
Second Decision	2024-04-18 02:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-18 07:11
Articles in Press	2024-04-18 07:11
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-04-23 19:50
Typeset the Manuscript

ISSN	2219-2808 (online)
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