Publication Name	World Journal of Clinical Oncology
Manuscript ID	91772
Country	India

Category	Oncology
Manuscript Type	Editorial
Article Title	Navigating breast cancer brain metastasis: Risk factors, prognostic indicators, and treatment perspectives
Manuscript Source	Invited Manuscript
All Author List	Jayalingappa Karthik, Amit Sehrawat, Mayank Kapoor and Deepak Sundriyal
Funding Agency and Grant Number
Corresponding Author	Amit Sehrawat, DNB, MBBS, MD, Associate Professor, Department of Medical Oncology Haematology, All India Institute of Medical Sciences Rishikesh, Virbhadra Road, Rishikesh 249203, Uttarakhand, India. dramitsehrawat@gmail.com
Key Words	Breast cancer; Brain metastasis; HER2 positive; Metastatic breast cancer; Risk factors, Predictive models
Core Tip	Breast cancer brain metastasis management faces many challenges. Key risk factors include HER-2 positivity, triple-negative subtype, and germline BRCA mutation. Limited predictive models emphasize the need for validated nomograms. Current guidelines recommend screening when symptomatic. Chen et al highlight HER-2 and triple-negative associations, impacting treatment strategies. Proactive research is crucial for preventive strategies, blood-brain barrier-penetrating therapies, and validated predictive models.
Citation	Karthik J, Sehrawat A, Kapoor M, Sundriyal D. Navigating breast cancer brain metastasis: Risk factors, prognostic indicators, and treatment perspectives. World J Clin Oncol 2024; In press

Received	2024-01-05 15:59
Peer-Review Started	2024-01-05 15:59
To Make the First Decision
Return for Revision	2024-01-17 02:45
Revised	2024-01-24 13:24
Second Decision	2024-04-15 02:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-15 07:58
Articles in Press	2024-04-15 07:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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