Publication Name	World Journal of Clinical Cases
Manuscript ID	91853
Country	Italy

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Treatment for paraganglioma with stereotactic radiotherapy
Manuscript Source	Invited Manuscript
All Author List	Antonio Pontoriero, Paola Critelli, Marco Zeppieri, Filippo Flavio Angileri and Tamara Ius
Funding Agency and Grant Number
Corresponding Author	Marco Zeppieri, BSc, MD, PhD, Doctor, Department of Ophthalmology, University Hospital of Udine, p.le S. Maria della Misericordia 15, Udine 33100, Italy. markzeppieri@hotmail.com
Key Words	Unresectable paraganglioma; Fractionated stereotactic radiation therapy; Cyberknife; Neurosurgery; Metastasis
Core Tip	Paragangliomas (PGs) are rare tumors with neuroendocrine origin. These lesions tend to be highly vascular and embryologically arise from the extra-adrenal autonomic nervous system, located in the thoracic, abdominal, and head-neck regions. PGs are usually sporadic, except in a few cases that are genetically determined by gene mutations. The clinical signs and symptoms include pulsatile tinnitus, headache, hearing loss, vocal fold paresis, vertigo, lower cranial nerve palsies, and tachycardias. Radiographic studies are pathognomonic in diagnosis. Treatment with fractionated stereotactic radiation therapy can be an effective option for these lesions, especially in reserving facial nerve function.
Citation	Pontoriero A, Critelli P, Zeppieri M, Angileri FF, Ius T. Treatment for paraganglioma with stereotactic radiotherapy. World J Clin Cases 2024; In press

Received	2024-01-07 11:16
Peer-Review Started	2024-01-07 11:16
To Make the First Decision
Return for Revision	2024-03-30 20:15
Revised	2024-04-08 10:30
Second Decision	2024-04-19 02:41
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-19 08:42
Articles in Press	2024-04-19 08:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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