Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	92029
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Endoscopic full-thickness plication along with argon plasma coagulation for treatment of proton pump inhibitor dependent gastroesophageal reflux disease
Manuscript Source	Unsolicited Manuscript
All Author List	Yogesh Harwani, Shreya Butala, Balaji More, Varun Shukla and Anand Patel
Funding Agency and Grant Number
Corresponding Author	Balaji More, MD, Associate Professor, Department of Pharmacology, Mahatma Gandhi Medical College and Research Institute, Puducherry 607402, Puducherry, India. drbdmore@gmail.com
Key Words	Gastroesophageal reflux disease; Endoscopy; Quality of life; Endoscopic antireflux interventions; Retrospective data analysis; GERD symptom scores; Proton pump inhibitor
Core Tip	The findings of this study are clinically relevant as they demonstrate that the endoscopic full-thickness fundoplication with argon plasma coagulation (APC) procedure leads to significant improvements in gastroesophageal reflux disease (GERD) symptoms and patients' quality of life, fibrosis post APC also helps in preventing suture dehiscence. The reduction in heartburn and regurgitation scores, as well as the overall gastroesophageal reflux disease health-related quality of life scores, signifies a positive impact on the subjective experience of patients with GERD. Moreover, the substantial decrease in proton pump inhibitor (PPI) usage, with a notable percentage of patients not requiring PPIs or prokinetics at 12 months, suggests a potential shift in the management paradigm towards more effective and sustainable alternatives.
Citation	Harwani Y, Butala S, More B, Shukla V, Patel A. Endoscopic full-thickness plication along with argon plasma coagulation for treatment of proton pump inhibitor dependent gastroesophageal reflux disease. World J Gastrointest Endosc 2024; In press

Received	2024-01-13 07:22
Peer-Review Started	2024-01-13 07:22
To Make the First Decision
Return for Revision	2024-01-23 18:27
Revised	2024-02-28 08:26
Second Decision	2024-04-25 02:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-25 08:52
Articles in Press	2024-04-25 08:52
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ISSN	1948-5190 (online)
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