Publication Name	World Journal of Experimental Medicine
Manuscript ID	92343
Country	China

Category	Biochemical Research Methods
Manuscript Type	Minireviews
Article Title	Potential and application of abortive transcripts as a novel molecular marker of cancers
Manuscript Source	Invited Manuscript
All Author List	Tian-Miao Zhang, Xiao-Nian Zhu, Shao-Wei Qin, Xue-Feng Guo, Xue-Kun Xing, Li-Feng Zhao and Sheng-Kui Tan
Funding Agency and Grant Number	Funding Agency Grant Number Key Science and Technology Research and Development Program Project of Guangxi AB22035017
Corresponding Author	Sheng-Kui Tan, MD, Professor, Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, Guilin Medical University, No. 1 Zhiyuan Road, Guilin 541199, Guangxi Zhuang Autonomous Region, China. sktan2008@sina.cn
Key Words	Abortive transcript; Abortive initiation; RNA polymerase; Transcription; Tumor marker
Core Tip	Abortive transcript (AT), as a special non-coding RNA, is the transcription product of abortive initiation. Abortive initiation occurs before normal transcription initiation and may be influenced by many factors. If its expression can be monitored normally, it will be of great significance for diagnosis and treatment of cancer. Though there are many difficulties and challenges in the study of AT in diseases, in-depth exploration of the role and mechanism of AT in cancers will provide a new potential target for early diagnosis and treatment of cancers and clinical prognosis.
Citation	<p>Zhang TM, Zhu XN, Qin SW, Guo XF, Xing XK, Zhao LF, Tan SK. Potential and application of abortive transcripts as a novel molecular marker of cancers. <i>World J Exp Med</i> 2024; 14(2): 92343</p>

Received	2024-01-23 04:09
Peer-Review Started	2024-01-23 04:09
To Make the First Decision
Return for Revision	2024-04-11 04:08
Revised	2024-04-25 10:28
Second Decision	2024-05-13 02:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-05-14 00:46
Articles in Press	2024-05-14 00:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-06-07 01:15

ISSN	2220-315x (online)
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