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Publication Name World Journal of Experimental Medicine
Manuscript ID 92343
Country China
Category Biochemical Research Methods
Manuscript Type Minireviews
Article Title Potential and application of abortive transcripts as a novel molecular marker of cancers
Manuscript Source Invited Manuscript
All Author List Tian-Miao Zhang, Xiao-Nian Zhu, Shao-Wei Qin, Xue-Feng Guo, Xue-Kun Xing, Li-Feng Zhao and Sheng-Kui Tan
Funding Agency and Grant Number
Funding Agency Grant Number
Key Science and Technology Research and Development Program Project of Guangxi AB22035017
Corresponding Author Sheng-Kui Tan, MD, Professor, Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, Guilin Medical University, No. 1 Zhiyuan Road, Guilin 541199, Guangxi Zhuang Autonomous Region, China. sktan2008@sina.cn
Key Words Abortive transcript; Abortive initiation; RNA polymerase; Transcription; Tumor marker
Core Tip Abortive transcript (AT), as a special non-coding RNA, is the transcription product of abortive initiation. Abortive initiation occurs before normal transcription initiation and may be influenced by many factors. If its expression can be monitored normally, it will be of great significance for diagnosis and treatment of cancer. Though there are many difficulties and challenges in the study of AT in diseases, in-depth exploration of the role and mechanism of AT in cancers will provide a new potential target for early diagnosis and treatment of cancers and clinical prognosis.
Citation Zhang TM, Zhu XN, Qin SW, Guo XF, Xing XK, Zhao LF, Tan SK. Potential and application of abortive transcripts as a novel molecular marker of cancers . World J Exp Med 2024; In press
Received
2024-01-23 04:09
Peer-Review Started
2024-01-23 04:09
To Make the First Decision
Return for Revision
2024-04-11 04:08
Revised
2024-04-25 10:28
Second Decision
2024-05-13 02:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2024-05-14 00:46
Articles in Press
2024-05-14 00:46
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Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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