Publication Name	World Journal of Stem Cells
Manuscript ID	92572
Country	China

Category	Pharmacology & Pharmacy
Manuscript Type	Basic Study
Article Title	Effect of ginsenoside Rg1 on hematopoietic stem cells in treating aplastic anemia in mice via MAPK pathway
Manuscript Source	Unsolicited Manuscript
All Author List	Jin-Bo Wang, Ming-Wei Du and Yan Zheng
Funding Agency and Grant Number	Funding Agency Grant Number Hangzhou Municipal Bureau of Science and Technology 2021WJCY366
Corresponding Author	Yan Zheng, MMed, Staff Physician, Department of Hepatic, The Xixi Hospital of Hangzhou Affiliated to Zhejiang University of Traditional Chinese Medicine, No. 2 Hengbu Street, Liuliu Town, Xihu District, Hangzhou 310023, Zhejiang Province, China. zjhzzygood@163.com
Key Words	Aplastic anemia; Ginsenoside Rg1; Myelosuppression; MAPK signaling pathway; Bone marrow; Hematopoietic stem cells
Core Tip	This study evaluates ginsenoside Rg1’s efficacy in aplastic anemia (AA) treatment, focusing on its impact on bone marrow pathology, hematopoiesis, and inflammation in a cyclophosphamide-induced myelosuppression C57 mice model. It demonstrates that ginsenoside Rg1 not only reduces cell apoptosis and inflammation but also promotes hematopoietic recovery by inhibiting the MAPK signaling pathway, offering a potential therapeutic strategy for AA.
Citation	<p>Wang JB, Du MW, Zheng Y. Effect of ginsenoside Rg1 on hematopoietic stem cells in treating aplastic anemia in mice via MAPK pathway. <i>World J Stem Cells</i> 2024; 16(5): 591-603</p>

Received	2024-01-30 04:03
Peer-Review Started	2024-01-30 04:03
To Make the First Decision
Return for Revision	2024-02-07 06:16
Revised	2024-02-20 08:17
Second Decision	2024-03-21 02:51
Accepted by Journal Editor-in-Chief	2024-03-24 05:47
Accepted by Executive Editor-in-Chief	2024-04-02 03:10
Articles in Press	2024-04-02 03:10
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-04-06 22:59
Typeset the Manuscript	2024-05-13 09:18

ISSN	1948-0210 (online)
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