Publication Name	World Journal of Transplantation
Manuscript ID	92721
Country	United States

Category	Transplantation
Manuscript Type	Minireviews
Article Title	Evolution of heart transplant donor characteristics in the 21st century: A United States single center’s experience
Manuscript Source	Unsolicited Manuscript
All Author List	Alexander M Spring, Christiana Gjelaj, Shivank Madan, Snehal R Patel, Omar Saeed, Sandhya Murthy, Yogita Rochlani, Daniel B Sims, Sasha Vukelic, Stephen J Forest, Jamil F Borgi, Daniel J Goldstein and Ulrich P Jorde
Funding Agency and Grant Number
Corresponding Author	Ulrich P Jorde, MD, Doctor, Professor, Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, MMC-MAP Room 7, Bronx, NY 10467, United States. ujorde@montefiore.org
Key Words	Orthotopic heart transplantation; Hepatitis C virus; COVID-19; Left ventricular systolic dysfunction; Human immunodeficiency virus; Donation after cardiac death
Core Tip	Since the turn of the 21st century, advances in certain laboratory studies, pharmacologic interventions, and organ care systems have led to the expansion of the donor pool in the field of orthotopic heart transplantation. This includes: (1) Nucleic acid testing and direct acting antivirals for donors with hepatitis C virus; (2) Organ care systems for donors who meet criteria for donation after cardiac death; (3) Anti-viral therapies for donors with coronavirus disease 19; (4) Improved donor management for grafts with left ventricular systolic dysfunction; and (5) Better understanding of immunosuppression and medication interaction in patients with human immunodeficiency virus. We detail how these advances have allowed our center to expand the donor pool thereby increasing transplantation volume without adverse effects on outcomes.
Citation	<p>Spring AM, Gjelaj C, Madan S, Patel SR, Saeed O, Murthy S, Rochlani Y, Sims DB, Vukelic S, Forest SJ, Borgi JF, Goldstein DJ, Jorde UP. Evolution of heart transplant donor characteristics in the 21st century: A United States single center’s experience. <i>World J Transplant</i> 2024; 14(3): 92721</p>

Received	2024-02-03 19:54
Peer-Review Started	2024-02-03 19:54
To Make the First Decision
Return for Revision	2024-04-19 06:21
Revised	2024-05-03 02:16
Second Decision	2024-06-07 02:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-06-07 09:46
Articles in Press	2024-06-07 09:46
Publication Fee Transferred	2024-06-10 12:54
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-07-17 14:25

ISSN	2220-3230 (online)
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