Publication Name	World Journal of Clinical Cases
Manuscript ID	92822
Country	United States

Category	Pathology
Manuscript Type	Case Report
Article Title	Congophilic fibrils in the glomeruli with polyclonal immunoglobulin gamma staining - another cause for diagnostic overlap: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Maria Bernadette Che-Ying Chow, Lucas Bushrow, Irmeen Siddiqui, April Chiu, Mirza Hamirani and Anjali A Satoskar
Funding Agency and Grant Number
Corresponding Author	Anjali A Satoskar, MD, Professor, Department of Pathology, The Ohio State University Medical Center, B073 Graves Hall 333 W 10th Ave, Columbus, OH 43210, United States. anjali.satoskar@osumc.edu
Key Words	Heavy and light chain amyloid; Fibrillary glomerulonephritis; DNAJB9; Serum immunofixation; Protein electrophoresis; Mass spectrometry; Congo red; Case report
Core Tip	Amyloidosis and fibrillary glomerulonephritis are the two most commonly encountered glomerulopathies with fibrillary deposits. Accurate diagnosis and differentiation between these two entities are important for patient management. Furthermore, accurate subtyping is also required for amyloidosis cases to further guide treatment. This case report highlights an uncommon diagnostic pitfall that a nephropathologist may encounter while distinguishing light and heavy chain amyloid from fibrillary glomerulopathy. The possible underlying mechanisms are discussed, and we reiterate the importance of a clinical-pathological correlation and the use of multiple available diagnostic modalities if needed, particularly for these overlapping diagnostic entities.
Citation	Chow MBCY, Bushrow L, Siddiqui I, Chiu A, Hamirani M, Satoskar AA. Congophilic fibrils in the glomeruli with polyclonal immunoglobulin gamma staining - another cause for diagnostic overlap: A case report. World J Clin Cases 2024; In press

Received	2024-02-06 23:43
Peer-Review Started	2024-02-07 03:06
To Make the First Decision
Return for Revision	2024-03-05 20:14
Revised	2024-03-15 22:34
Second Decision	2024-04-23 02:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-23 09:31
Articles in Press	2024-04-23 09:31
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ISSN	2307-8960 (online)
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