Publication Name	World Journal of Diabetes
Manuscript ID	92975
Country	Malaysia

Category	Endocrinology & Metabolism
Manuscript Type	Review
Article Title	Insulin resistance as the molecular link between diabetes and Alzheimer's disease
Manuscript Source	Invited Manuscript
All Author List	Mona Mohamed Ibrahim Abdalla
Funding Agency and Grant Number
Corresponding Author	Mona Mohamed Ibrahim Abdalla, MSc, PhD, Senior Lecturer, Department of Human Biology, School of Medicine, International Medical University, No. 126, Jln Jalil Perkasa 19, Bukit Jalil 57000, Kuala Lumpur, Malaysia. monamohamed@imu.edu.my
Key Words	Alzheimer's disease; Insulin resistance; Obesity; Dementia; Diabetes; Metabolic syndrome
Core Tip	Insulin resistance (IR), commonly associated with type 2 diabetes, is a crucial factor linking diabetes mellitus to Alzheimer's disease (AD). While insulin is primarily known for regulating blood sugar, it also plays a significant role in brain health. Dysfunctional insulin signaling, characteristic of IR, adversely impacts brain functions and is implicated in the development of AD's defining features, such as beta-amyloid plaques and tau protein tangles. Understanding and addressing IR early could offer new treatment strategies for AD, highlighting the importance of continued research in this interdisciplinary field.
Citation	Abdalla MMI. Insulin resistance as the molecular link between diabetes and Alzheimer's disease. World J Diabetes 2024; In press

Received	2024-02-14 13:14
Peer-Review Started	2024-02-14 13:14
To Make the First Decision
Return for Revision	2024-03-05 02:52
Revised	2024-04-08 07:32
Second Decision	2024-04-16 09:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-05-06 06:13
Articles in Press	2024-05-06 06:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com