Publication Name	World Journal of Psychiatry
Manuscript ID	93113
Country	China

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Retrospective Study
Article Title	Clinical intervention effect of Xuefu Zhuyu decoction on chronic heart failure complicated with depression
Manuscript Source	Unsolicited Manuscript
All Author List	Ying Wang, Jun Wang, Wang Lv, Hu Chen, Qian Yang, Yang Zhang, Run Guo, Xiao-Li Ma and Qian-Yu Zhang
Funding Agency and Grant Number	Funding Agency Grant Number Scientific Research Plan Project of Hebei Provincial Administration of Traditional Chinese Medicine 2018507
Corresponding Author	Ying Wang, MM, Doctor, Department of Traditional Chinese Medicine, Cangzhou Central Hospital, No. 16 Xinhua West Road, Cangzhou 061000, Hebei Province, China. wangying_30@126.com
Key Words	Xuefu Zhuyu decoction; Chronic heart failure; Depression; Cardiac function; Negative emotions
Core Tip	Chronic heart failure (CHF) is a hemodynamic disorder that leads to systolic and diastolic dysfunction and increases the risk of diabetes and chronic kidney disease. Additionally, the risk of depression in patients with CHF can reach up to 60%, and the diagnosis and treatment of depression in this patient population is challenging because there is no ideal therapy for this comorbidity. This study comparatively analyzed the clinical effects of Xuefu Zhuyu decoction (XFZYD) vs Western medicine in patients with CHF complicated with depression from the perspectives of clinical efficacy, traditional Chinese medicine symptom score, cardiac function, negative emotions, and serum inflammatory factor levels. We found that the clinical efficacy of XFZYD was significantly higher than Western medicine for treating CHF complicated with depression and significantly reduced patients’ symptoms, improved cardiac function, alleviated negative emotions, and inhibited serum inflammatory factors. Therefore, XFZYD is highly beneficial for improving the efficacy and clinical outcomes of patients with CHF complicated with depression.
Citation	Wang Y, Wang J, Lv W, Chen H, Yang Q, Zhang Y, Guo R, Ma XL, Zhang QY. Clinical intervention effect of Xuefu Zhuyu decoction on chronic heart failure complicated with depression. World J Psychiatry 2024; In press

Received	2024-02-28 10:42
Peer-Review Started	2024-02-28 10:42
To Make the First Decision
Return for Revision	2024-04-13 11:03
Revised	2024-05-06 01:42
Second Decision	2024-05-08 02:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-05-08 05:02
Articles in Press	2024-05-08 05:02
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Typeset the Manuscript

ISSN	2220-3206 (online)
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