Publication Name	World Journal of Stem Cells
Manuscript ID	93132
Country	Saudi Arabia

Category	Cell & Tissue Engineering
Manuscript Type	Editorial
Article Title	Mesenchymal stem cells’ “garbage bags” at work: Treating radial nerve injury with mesenchymal stem cell-derived exosomes
Manuscript Source	Invited Manuscript
All Author List	Mazhar Mushtaq, Doaa Hussein Zineldeen, Muhammad Abdul Mateen and Khawaja Husnain Haider
Funding Agency and Grant Number
Corresponding Author	Khawaja Husnain Haider, BPharm, BSc, PhD, Chairman, Full Professor, Department of Basic Sciences, Sulaiman AlRajhi University, AlMadina Road, Albukairiyah 52736, AlQaseem, Saudi Arabia. kh.haider@sr.edu.sa
Key Words	Exosome; Mesenchymal stem cells; Nerve injury; Stem cells; Secretome; Regeneration
Core Tip	The extracellular vesicles constituting the insoluble component of the secretome were once considered cell’s garbage bags. They have become a hot area of research since realizing their significance as an essential means of intracellular communication. They have shown promise for therapeutic applications for repairing and regenerating the damaged tissues via delivering their payload to the resident reparative cells and supporting them in the intrinsic repair process. Although stem cell-derived exosomes have been extensively studied for peripheral nerve injury repair in experimental animal models, their use for radial nerve injury repair in a patient, as the pilot study by Civelek et al, is expected to pave the way for assessment in future clinical trials.
Citation	Mushtaq M, Zineldeen DH, Mateen MA, Haider KH. Mesenchymal stem cells’ “garbage bags” at work: Treating radial nerve injury with mesenchymal stem cell-derived exosomes. World J Stem Cells 2024; In press

Received	2024-02-20 11:18
Peer-Review Started	2024-02-21 00:25
To Make the First Decision
Return for Revision	2024-03-31 03:46
Revised	2024-04-03 14:51
Second Decision	2024-04-25 02:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-25 08:00
Articles in Press	2024-04-25 08:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
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