Publication Name	World Journal of Stem Cells
Manuscript ID	93183
Country	Italy

Category	Biochemistry & Molecular Biology
Manuscript Type	Editorial
Article Title	Deer antler stem cell niche: An interesting perspective
Manuscript Source	Invited Manuscript
All Author List	Claudia Cavallini, Elena Olivi, Riccardo Tassinari, Chiara Zannini, Gregorio Ragazzini, Martina Marcuzzi, Valentina Taglioli and Carlo Ventura
Funding Agency and Grant Number
Corresponding Author	Carlo Ventura, MD, PhD, Director, Full Professor, National Laboratory of Molecular Biology and Stem Cell Engineering, National Institute of Biostructures and Biosystems - Eldor Lab, Via Corticella 183, Bologna 40128, Italy. carlo.ventura@unibo.it
Key Words	Extracellular matrix; Antler stem cells; Stem cell niche; Regenerative medicine or tissue regeneration; Decellularized scaffolds; Cell memory
Core Tip	Recent research has focused on enhancing cell regenerative capacity through biomaterials, particularly natural scaffolds. A novel study published in World J Stem Cells investigates the possibility of using a decellularized xenogeneic extracellular matrix (ECM) from antler stem cells to repair osteochondral defects in rats. Our editorial emphasizes the vital role of biological scaffolds in boosting stem cell potential and regenerative abilities by creating a favorable microenvironment. Stem cell differentiation relies on the ECM properties, including its chemical composition and mechanical forces. This bio-instructive signaling environment offers tissue-specific guidance for effective repair and regeneration, aligning with the growing interest in mechanobiology.
Citation	Cavallini C, Olivi E, Tassinari R, Zannini C, Ragazzini G, Marcuzzi M, Taglioli V, Ventura C. Deer antler stem cell niche: An interesting perspective. World J Stem Cells 2024; In press

Received	2024-02-21 11:29
Peer-Review Started	2024-02-21 11:29
To Make the First Decision
Return for Revision	2024-03-31 03:45
Revised	2024-04-09 11:05
Second Decision	2024-04-25 02:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-25 07:53
Articles in Press	2024-04-25 07:53
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Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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