Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	93201
Country	United States

Category	Surgery
Manuscript Type	Editorial
Article Title	Non-operative management of rectal cancer: Highlighting the controversies
Manuscript Source	Invited Manuscript
All Author List	Sameh Hany Emile and Anjelli Wignakumar
Funding Agency and Grant Number
Corresponding Author	Sameh Hany Emile, FACS, MD, MSc, PhD, Associate Professor, Research Scientist, Surgeon, Department of Colorectal Surgery, Cleveland Clinic Florida, No. 2950 Cleveland Clinic Blvd, Weston, FL 33331, United States. sameh200@hotmail.com
Key Words	Non-operative; Management; Rectal cancer; Highlighting; Controversies
Core Tip	Patients with locally advanced rectal cancers are ideally treated with neoadjuvant chemoradiation therapy followed by surgical resection. As neoadjuvant treatments evolved, an increasing number of patients showed a complete response to neoadjuvant therapy. The complete response of rectal cancers to neoadjuvant treatment inspired the concept of non-operative management (NOM). Following extensive multidisciplinary team meeting discussion, patients can be considered for NOM. Questions arose regarding patient selection for NOM and the best surveillance program to ensure no red flags for recurrent disease. Another consideration is how patients who develop recurrence be managed.
Citation	Emile SH, Wignakumar A. Non-operative management of rectal cancer: Highlighting the controversies. World J Gastrointest Surg 2024; In press

Received	2024-02-21 15:17
Peer-Review Started	2024-02-21 15:17
To Make the First Decision
Return for Revision	2024-04-17 08:08
Revised	2024-04-18 13:39
Second Decision	2024-04-23 02:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-23 06:55
Articles in Press	2024-04-23 06:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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