Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	93341
Country	Egypt

Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Fecal calprotectin in pediatric gastrointestinal diseases: Pros and cons
Manuscript Source	Invited Manuscript
All Author List	Mohammed Al-Beltagi, Nermin Kamal Saeed, Adel Salah Bediwy and Reem Elbeltagi
Funding Agency and Grant Number
Corresponding Author	Mohammed Al-Beltagi, MBChB, MD, PhD, Academic Editor, Chairman, Professor, Research Scientist, Department of Pediatric , Faculty of Medicine, Tanta University, Al-Bahr street, The Medical Complex, Tanta ‎ 31511‎, Alghrabia, Egypt. mbelrem@hotmail.com
Key Words	Fecal calprotectin; Pediatric gastrointestinal diseases; Functional gastrointestinal ‎disorders; Inflammatory bowel disease; Coeliac disease; COVID-19-induced ‎gastrointestinal disorders; Infectious gastroenteritis; Cystic fibrosis
Core Tip	The core findings of this systematic review underscore the pivotal role of fecal calprotectin as a non-invasive marker for assessing intestinal inflammation in pediatric gastrointestinal diseases. Through an extensive systematic literature review, it was evident that fecal calprotectin provides valuable insights into disease activity, treatment response, and prognosis across various conditions, including functional gastrointestinal disorders, inflammatory bowel disease, coeliac disease, coronavirus disease 2019 induced gastrointestinal disorders, gastroenteritis, and cystic fibrosis-associated intestinal pathology. Despite its limitations in specificity and susceptibility to confounding factors, fecal calprotectin remains a valuable tool in pediatric gastroenterology, offering clinicians a means to diagnose, monitor, and manage gastrointestinal diseases effectively.
Citation	<p>Al-Beltagi M, Saeed NK, Bediwy AS, Elbeltagi R. Fecal calprotectin in pediatric gastrointestinal diseases: Pros and cons. <i>World J Clin Pediatr</i> 2024; 13(2): 93341</p>

Received	2024-02-25 10:42
Peer-Review Started	2024-02-25 10:42
To Make the First Decision
Return for Revision	2024-04-19 18:07
Revised	2024-04-28 09:05
Second Decision	2024-05-13 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-05-14 00:53
Articles in Press	2024-05-14 00:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-14 08:28

ISSN	2219-2808 (online)
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