Publication Name	World Journal of Gastroenterology
Manuscript ID	93404
Country	Italy

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Metadherin-driven promotion of cancer stem cell phenotypes and its effect on immunity in hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Nevena Todorović and Amedeo Amedei
Funding Agency and Grant Number
Corresponding Author	Amedeo Amedei, MSc, Full Professor, Department of Experimental and Clinical Medicine, University of Florence, 3 Largo Brambilla, Florence 50134, Italy. amedeo.amedei@unifi.it
Key Words	Hepatocellular carcinoma; Metadherin; Astrocyte elevated gene-1; Lysine rich CEACAM1; Cancer stem cell; Immunity
Core Tip	Metadherin (MTDH) is a protein and a predictor of poor prognosis, of aggressive tumor phenotypes prone to metastasis, recurrence, and therapy resistance in hepatocellular carcinoma (HCC). Several studies have demonstrated a correlation between MTDH and cancer stem cells, which has elevated interest in further investigating this oncogene and its impacts to a higher level. The editorial highlights the ongoing research in the HCC field, revealing the significance for future studies.
Citation	<p>Todorović N, Amedei A. Metadherin-driven promotion of cancer stem cell phenotypes and its effect on immunity in hepatocellular carcinoma. <i>World J Gastroenterol</i> 2024; 30(20): 2624-2628</p>

Received	2024-02-29 09:43
Peer-Review Started	2024-02-29 09:43
To Make the First Decision
Return for Revision	2024-04-18 21:16
Revised	2024-04-24 16:05
Second Decision	2024-05-09 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-05-09 03:06
Articles in Press	2024-05-09 03:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-27 15:42

ISSN	1007-9327 (print) and 2219-2840 (online)
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