Publication Name	World Journal of Gastroenterology
Manuscript ID	93597
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Liver transplantation following two conversions in a patient with huge hepatocellular carcinoma and portal vein invasion: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Li-Cong Liang, Wen-Sou Huang, Zhao-Xiong Guo, Hong-Ji You, Yong-Jian Guo, Ming-Yue Cai, Li-Teng Lin, Guo-Ying Wang and Kang-Shun Zhu
Funding Agency and Grant Number
Corresponding Author	Kang-Shun Zhu, MD, PhD, Director, Doctor, Professor, Department of Minimally Invasive Interventional Radiology, The Second Affiliated Hospital of Guangzhou Medical University, No. 250 East Changgang Road, Guangzhou 510260, Guangdong Province, China. zhksh010@163.com
Key Words	Hepatocellular carcinoma; Two conversions; Liver transplantation; Yttrium-90 resin microspheres; Transarterial chemoembolization; Hepatic arterial infusion chemotherapy; Case report
Core Tip	We report a patient with > 20 cm hepatocellular carcinoma (HCC) and portal vein tumor thrombus (PVTT) who successfully received liver transplantation (LT) after two conversions. He was first converted to selective internal radiation therapy (SIRT) eligibility with transarterial chemoembolization and infusion chemotherapy combined with systemic therapy and then converted to LT with SIRT and continued systemic therapy. This is significant because few patients with huge (> 10 cm in diameter) HCC and PVTT can receive curative treatments or curative treatments after one conversion.
Citation	Liang LC, Huang WS, Guo ZX, You HJ, Guo YJ, Cai MY, Lin LT, Wang GY, Zhu KS. Liver transplantation following two conversions in a patient with huge hepatocellular carcinoma and portal vein invasion: A case report. World J Gastroenterol 2024; In press

Received	2024-03-02 14:05
Peer-Review Started	2024-03-02 14:06
To Make the First Decision
Return for Revision	2024-08-10 19:47
Revised	2024-08-23 13:46
Second Decision	2024-09-03 02:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-09-03 07:56
Articles in Press	2024-09-03 07:56
Publication Fee Transferred	2024-09-06 11:55
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Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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