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Publication Name World Journal of Clinical Cases
Manuscript ID 93679
Country China
Category Respiratory System
Manuscript Type Retrospective Study
Article Title Study on the efficacy of early treatment with pirfenidone on lung function of idiopathic pulmonary fibrosis patients
Manuscript Source Unsolicited Manuscript
All Author List Ying Lei, Jian-Hui Sheng, Xu-Ru Jin, Xian-Bing Liu, Xiao-Yan Zheng and Xiao-Hua Xu
Funding Agency and Grant Number
Corresponding Author Xiao-Hua Xu, MM, Researcher, Department of Pulmonary and Critical Care Medicine, The Quzhou Affiliate Hospital of Wenzhou Medical University, No. 100 Minjiang Avenue, Quzhou 324000, Zhejiang Province, China. xxh406302383@163.com
Key Words Pirfenidone; Early intervention; Idiopathic pulmonary fibrosis; Pulmonary function; Effect evaluation
Core Tip The purpose of this study was to assess the effects of pirfenidone in the early treatment of idiopathic pulmonary fibrosis (IPF) on lung function in patients. A retrospective analysis was conducted on 113 patients with IPF. These patients were categorized into two groups: A control group (n = 53) and an observation group (n = 60). In the control group, patients received routine therapy in combination with methylprednisolone tablets, while the observation group received routine therapy along with pirfenidone. Eventually we came to the conclusion that the prompt initiation of pirfenidone treatment in individuals diagnosed with idiopathic pulmonary fibrosis can enhance pulmonary function, elevate inflammatory factor levels, and increase the distance covered in the 6-minute walk test. This intervention is conducive to effectively decreasing the occurrence of adverse reactions in patients.
Citation Lei Y, Sheng JH, Jin XR, Liu XB, Zheng XY, Xu XH. Study on the efficacy of early treatment with pirfenidone on lung function of idiopathic pulmonary fibrosis patients. World J Clin Cases 2024; In press
2024-03-03 16:52
Peer-Review Started
2024-03-03 16:52
To Make the First Decision
Return for Revision
2024-04-22 20:01
2024-05-10 17:51
Second Decision
2024-06-06 02:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2024-06-07 08:57
Articles in Press
2024-06-07 08:57
Publication Fee Transferred
2024-06-13 15:17
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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