Publication Name	World Journal of Diabetes
Manuscript ID	94430
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Case Report
Article Title	Transient diabetes mellitus with ABCC8 variant successfully treated with sulfonylurea: Two case reports and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Ling-Hua Shen, Yan Cui, Dong-Xia Fu, Wei Yang, Sheng-Nan Wu, Hui-Zhen Wang, Hai-Hua Yang, Yong-Xing Chen and Hai-Yan Wei
Funding Agency and Grant Number	Funding Agency Grant Number Department of Science and Technology of Henan Province 222102310461
Corresponding Author	Hai-Yan Wei, MD, Chief Doctor, Department of Endocrinology and Metabolism, Henan Key Laboratory of Children's Genetics and Metabolic Diseases, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital Zhengzhou Children's Hospital, No. 33 Longhu Outer Ring East Road, Zhengdong New District, Zhengzhou 450018, Henan Province, China. haiyanwei2009@163.com
Key Words	Neonatal diabetes mellitus; ABCC8; Sulfonylurea receptors 1; KATP channels; Sulfonylurea; Glyburide; Insulin; Case report
Core Tip	Currently, no reports have described the c.3880C>T heterozygous variant of the ABCC8 gene in patients with diabetes mellitus. After identifying that this heterozygous variant can cause transient neonatal diabetes mellitus, we found that oral sulfonylurea therapy was safe and effective and could successfully replace insulin treatment in two patients with the c.3880C>T heterozygous variant of the ABCC8 gene. This genetic diagnosis will inform clinicians about the probable course and optimal management strategy for diabetes in these patients.
Citation	<p>Shen LH, Cui Y, Fu DX, Yang W, Wu SN, Wang HZ, Yang HH, Chen YX, Wei HY. Transient diabetes mellitus with ABCC8 variant successfully treated with sulfonylurea: Two case reports and review of literature. <i>World J Diabetes</i> 2024; 15(8): 1811-1819</p>

Received	2024-03-22 14:11
Peer-Review Started	2024-03-22 14:11
To Make the First Decision
Return for Revision	2024-05-11 08:12
Revised	2024-05-24 19:10
Second Decision	2024-06-11 06:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-18 08:17
Articles in Press	2024-06-18 08:17
Publication Fee Transferred	2024-06-19 23:26
Edit the Manuscript by Language Editor	2024-06-26 23:02
Typeset the Manuscript	2024-06-29 15:45

ISSN	1948-9358 (online)
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