Publication Name	World Journal of Clinical Cases
Manuscript ID	94923
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Review of the potential value of serum interleukin levels as prognostic biomarkers of liver failure
Manuscript Source	Unsolicited Manuscript
All Author List	Yong Lin, Geng-Jie Yan, Mei-Yan Liu, Yin Cao, Kan Zhang, Na Wang, Fu-Li Long and De-Wen Mao
Funding Agency and Grant Number	Funding Agency Grant Number The National Natural Science Foundation of China 82260907, 82260899, 82274434
Corresponding Author	De-Wen Mao, Doctor, MD, PhD, Doctor, Doctor, Professor, Teacher, Department of Hepatology, The First Affiliated Hospital of Guangxi University of Chinese Medicine, No. 89-9 Dongge Road, Nanning 530023, Guangxi Zhuang Autonomous Region, China. mdwboshi2005@163.com
Key Words	Interleukin-21; Interleukin-22; Interleukin-31; Liver failure; Biological markers; Potential value
Core Tip	This review highlights the potential of interleukins (ILs), particularly IL-21, IL-22, and IL-31, as the prognostic biomarkers of liver failure. The article emphasizes the crucial role of immune responses in liver failure pathogenesis and explores the complex interplay between these ILs and various immune cells, signaling pathways, and liver diseases. Moreover, it critically analyzes existing literature, identifying limitations and suggesting future directions for further research.
Citation	<p>Lin Y, Yan GJ, Liu MY, Cao Y, Zhang K, Wang N, Long FL, Mao DW. Review of the potential value of serum interleukin levels as prognostic biomarkers of liver failure. <i>World J Clin Cases</i> 2024; 12(27): 6045-6056</p>

Received	2024-03-28 02:51
Peer-Review Started	2024-03-28 02:51
To Make the First Decision
Return for Revision	2024-06-24 10:37
Revised	2024-07-03 13:39
Second Decision	2024-07-10 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-10 08:53
Articles in Press	2024-07-10 08:53
Publication Fee Transferred	2024-07-11 09:18
Edit the Manuscript by Language Editor	2024-07-20 21:43
Typeset the Manuscript	2024-07-24 03:16

ISSN	2307-8960 (online)
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