Publication Name	World Journal of Clinical Cases
Manuscript ID	95067
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Efficacy and safety of Xileisan combined with mesalazine for ulcerative colitis: A meta-analysis and trial sequential analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Xin-Yu Yang, Yun-Feng Yu, Ke-Ke Tong, Gang Hu, Rong Yu and Lian-Jun Su
Funding Agency and Grant Number	Funding Agency Grant Number Discipline Construction Project of Hunan University of Chinese Medicine 22JBZ002
Corresponding Author	Lian-Jun Su, Doctor, N/A, School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, No. 300, Xueshi Road, Hanpu Science and Education Park, Yuelu District, Changsha 410208, Hunan Province, China. sulianjun@hnucm.edu.cn
Key Words	Xileisan; Mesalazine; Ulcerative colitis; Meta-analysis; Trial sequential analysis
Core Tip	The benefits and potential risks of Xileisan (XLS) in the treatment of ulcerative colitis (UC) remain unclear. The present study aimed to evaluate the efficacy and safety of XLS combined with mesalazine in the treatment of UC through meta-analysis and trial sequential analysis. The meta-analysis showed that XLS alleviated the clinical symptoms, intestinal mucosal injury, and inflammatory response in patients with UC, while demonstrating good safety. XLS, therefore, represents a safe and effective treatment strategy for UC.
Citation	<p>Yang XY, Yu YF, Tong KK, Hu G, Yu R, Su LJ. Efficacy and safety of Xileisan combined with mesalazine for ulcerative colitis: A meta-analysis and trial sequential analysis. <i>World J Clin Cases</i> 2024; 12(21): 4703-4716</p>

Received	2024-04-04 10:13
Peer-Review Started	2024-04-04 10:13
To Make the First Decision
Return for Revision	2024-05-01 02:37
Revised	2024-05-14 16:07
Second Decision	2024-06-06 02:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-06-07 09:10
Articles in Press	2024-06-07 09:10
Publication Fee Transferred	2024-06-14 11:07
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-06-26 00:34

ISSN	2307-8960 (online)
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