| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Jianpi-Huatan-Huoxue-Anshen ameliorates gastrointestinal inflammation and microecology in chemotherapy-treated mice transplanted with H22 hepatocellular carcinoma
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan-Nan Wang, Xiang-Yang Zhai, Zheng Wang, Chun-Ling Gao, Sui-Cai Mi, Wen-Li Tang, Xue-Min Fu, Huai-Bang Li, Li-Feng Yue, Peng-Fei Li and Sheng-Yan Xi |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Xiamen, China |
3502Z20227171 |
| the Young Investigator Research Program of Xiang’an Hospital of Xiamen University |
XAH23005 |
| the Traditional Chinese Medicine Foundation of Xiamen |
XWZY-2023-0103 |
| Natural Science Foundation of Fujian, China |
2018J01136 |
| National Natural Science Foundation of China |
81202659 |
|
| Corresponding Author |
Sheng-Yan Xi, Doctor, PhD, Associate Chief Physician, Associate Professor, Department of TCM, Xiang’an Hospital, School of Medicine, Xiamen University, No. 4221-122 Xiang’an Nan Road, Xiamen 361102, Fujian Province, China. xishengyan@xmu.edu.cn |
| Key Words |
Chinese medicine; Chemotherapy; H22 hepatocellular carcinoma; Intestinal barrier function; Intestinal microecological balance |
| Core Tip |
Jianpi-Huatan-Huoxue-Anshen formula (Tzu-Chi cancer-antagonizing & life-protecting II decoction) down-regulates NF-κB pathway and the release of inflammatory factors, alleviates intestinal inflammation, improves intestinal morphology, reduces intestinal barrier damage, and keeps the dynamic balance of intestinal microecology. These results reveal the potential role and advantages of Chinese herbal compounds in improving the unbalanced microenvironment after cancer chemotherapy. |
| Citation |
Wang YN, Zhai XY, Wang Z, Gao C, Mi SC, Tang WL, Fu XM, Li HB, Yue LF, Li PF, Xi SY. Jianpi-Huatan-Huoxue-Anshen ameliorates gastrointestinal inflammation and microecology in chemotherapy-treated mice transplanted with H22 hepatocellular carcinoma. World J Gastrointest Oncol 2024; In press |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
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|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
