Publication Name	World Journal of Clinical Cases
Manuscript ID	95319
Country	Bulgaria

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Interferon-gamma release assays as a tool for differential diagnosis of gastrointestinal tuberculosis
Manuscript Source	Invited Manuscript
All Author List	Tsvetelina Velikova and Anita Aleksandrova
Funding Agency and Grant Number	Funding Agency Grant Number The European Union-NextGenerationEU, through the National Recovery and Resilience Plan of the Republic of Bulgaria BG-RRP-2.004-0008
Corresponding Author	Anita Aleksandrova, MBBS, Medical Assistant, Department of Immunology, Medical-diagnostic laboratory Ramus, Georgi Dimitrov 44, Simitli 6000, Bulgaria. nikolovaanita96@gmail.com
Key Words	Tuberculosis; Gastrointestinal tuberculosis; Interferon-gamma release assay; IGRA; Primary gastroduodenal tuberculosis; Gastric outlet obstruction; Case report
Core Tip	The diagnosis of abdominal tuberculosis (TB) is frequently delayed since there are no identifiable clinical signs and symptoms, and the illness might resemble other intra-abdominal disorders. In line with this, the most prevalent causes of gastric outlet obstruction are peptic ulcer disease and stomach cancer, and when excluded, TB infection should be added as a differential diagnosis. Assays of interferon-gamma release (IGRAs) have become a crucial diagnostic tool for latent TB infection. IGRAs have also been used to potentially distinguish between mimics such as Crohn's disease or other ascites-causing conditions and abdominal TB. Given that they are unaffected by the Bacille Calmette-Guérin immunization, these are considered beneficial.
Citation	Velikova T, Aleksandrova A. Interferon-gamma release assays as a tool for differential diagnosis of gastrointestinal tuberculosis. World J Clin Cases 2024; In press

Received	2024-04-07 21:01
Peer-Review Started	2024-04-07 21:01
To Make the First Decision
Return for Revision	2024-05-09 05:19
Revised	2024-05-12 19:11
Second Decision	2024-06-07 02:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-06-07 09:14
Articles in Press	2024-06-07 09:14
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-06-24 01:04
Typeset the Manuscript

ISSN	2307-8960 (online)
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