Publication Name	World Journal of Diabetes
Manuscript ID	95542
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Basic Study
Article Title	Molecular mechanisms of Buqing granule for the treatment of diabetic retinopathy: Network pharmacology analysis and experimental validation
Manuscript Source	Unsolicited Manuscript
All Author List	Yi-Fan Yang, Ling Yuan, Xiang-Yang Li, Qian Liu, Wen-Jie Jiang, Tai-Qiang Jiao, Jia-Qing Li, Meng-Yi Ye, Yang Niu and Yi Nan
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81960836 Ningxia Natural Science Foundation 2020AAC03126 Ningxia Higher Education Scientific Research Project NGY2020045
Corresponding Author	Yi Nan, MD, Professor, Key Laboratory of Ningxia Minority Medicine Modernization Ministry of Education, Ningxia Medical University, No. 1160 Shengli Street, Yinchuan 750004, Ningxia Hui Autonomous Region, China. 20080011@nxmu.edu.cn
Key Words	Diabetic retinopathy; Network pharmacology; Animal models; Oxidative stress; Inflammatory
Core Tip	In this study, we constructed a diabetic retinopathy (DR) model in Sprague-Dawley rats and combined network pharmacology and in vivo experiments to thoroughly investigate the therapeutic efficacy of Buqing granule in DR and their mechanism of action. The experimental data showed that Buqing granule could significantly reduce oxidative stress and inflammatory damage, thus delaying DR. This finding not only deepens our understanding of DR pathogenesis, but also provides new ideas and potential therapeutic targets for future innovation in DR treatment.
Citation	<p>Yang YF, Yuan L, Li XY, Liu Q, Jiang WJ, Jiao TQ, Li JQ, Ye MY, Niu Y, Nan Y. Molecular mechanisms of Buqing granule for the treatment of diabetic retinopathy: Network pharmacology analysis and experimental validation. <i>World J Diabetes</i> 2024; 15(9): 1942-1961</p>

Received	2024-04-12 07:20
Peer-Review Started	2024-04-12 07:20
To Make the First Decision
Return for Revision	2024-06-22 19:49
Revised	2024-07-05 08:22
Second Decision	2024-07-23 07:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-31 06:55
Articles in Press	2024-07-31 06:55
Publication Fee Transferred	2024-08-02 02:04
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-08-20 23:37

ISSN	1948-9358 (online)
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