Publication Name	World Journal of Meta-Analysis
Manuscript ID	95631
Country	United Kingdom

Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Blastocystis hominis as a cause of chronic diarrhea in low-resource settings: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Stephen Amoak and Jonathan Soldera
Funding Agency and Grant Number
Corresponding Author	Jonathan Soldera, MD, MSc, PhD, Instructor, Acute Medicine and Gastroenterology, University Of South Wales, Llantwit Rd, Pontypridd, Cardiff CF37 1DL, United Kingdom. jonathansoldera@gmail.com
Key Words	Blastocystis infections; Gastrointestinal diseases; Treatment outcome; Developing countries; Metronidazole/therapeutic use
Core Tip	This systematic review highlights the symptomatology and treatment outcomes of Blastocystis hominis (B. hominis) infection in low-resource settings. Notably, chronic diarrhea due to B. hominis is rare in these contexts. Abdominal pain, diarrhea, flatulence, constipation, and nausea/vomiting are the predominant symptoms reported. Post-treatment recovery rates are promising, ranging from 60% to 100% after two weeks of treatment. Metronidazole is recommended as the initial treatment, with consideration for alternative options if needed. These findings provide valuable insights for healthcare practitioners managing B. hominis infections in resource-limited settings.
Citation	Amoak S, Soldera J. Blastocystis hominis as a cause of chronic diarrhea in low-resource settings: A systematic review. World J Meta-Anal 2024; In press

Received	2024-04-14 19:38
Peer-Review Started	2024-04-14 19:38
To Make the First Decision
Return for Revision	2024-08-10 19:42
Revised	2024-08-24 00:25
Second Decision	2024-09-04 02:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-09-04 07:25
Articles in Press	2024-09-04 07:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2308-3840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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