Publication Name	World Journal of Meta-Analysis
Manuscript ID	95755
Country	Colombia

Category	Nuclear Science & Technology
Manuscript Type	Minireviews
Article Title	Fibroblast activation protein inhibitors positron emission tomography/computed tomography: Review of the literature
Manuscript Source	Invited Manuscript
All Author List	Nathalie Hernandez-Hidalgo, Gerardo Cortes, Klissman Ortega-Anaya and Humberto Varela
Funding Agency and Grant Number
Corresponding Author	Nathalie Hernandez-Hidalgo, MD, Academic Research, Doctor, Department of Nuclear Medicine, Instituto Nacional de Cancerologia, Cl.1#9-85, Bogota 111321, Colombia. nathaliehh2809@gmail.com
Key Words	Fibroblast activation protein inhibitors; Fibroblast activation protein; Positron emission tomography/computed tomography; Cancer
Core Tip	Fibroblast activation protein inhibitors (FAPI) has been a protagonist in the most recent research in the field of nuclear medicine and oncology, demonstrating surprising diagnostic versatility with a dizzying rise, due to its successful labeling with radioisotopes (Ga68 and F18). In the comparative clinical studies that have been carried out to date, it appears that FAPI is superior to fluorodeoxyglucose in oncological diagnostic performance, according to certain advantages it has, mainly related to a better lesion-to-background ratio, lower radiation dose, non-dependence on glucose level or preparatory diet, low brain uptake and its promising use as a theragnostic. FAPI positron emission tomography/computed tomography constitutes a great challenge to address for nuclear medicine and current oncology, which is approaching our present by leaps and bounds, possibly marking a new route in the approach and treatment of oncological diseases.
Citation	Hernandez-Hidalgo N, Cortes G, Ortega-Anaya K, Varela H. Fibroblast activation protein inhibitors positron emission tomography/computed tomography: Review of the literature. World J Meta-Anal 2024; In press

Received	2024-04-17 15:03
Peer-Review Started	2024-04-17 15:03
To Make the First Decision
Return for Revision	2024-05-16 00:49
Revised	2024-09-07 18:02
Second Decision	2024-09-30 02:53
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-30 07:04
Articles in Press	2024-09-30 07:04
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ISSN	2308-3840 (online)
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