Publication Name	World Journal of Hepatology
Manuscript ID	95763
Country	South Africa

Category	Surgery
Manuscript Type	Retrospective Study
Article Title	Clinicopathological presentation of liver abscesses and hydatid liver disease from two South African tertiary hospitals
Manuscript Source	Unsolicited Manuscript
All Author List	Krevosha Pillay, Zafar Ahmed Khan, Ekene Emmanuel Nweke and Jones Omoshoro-Jones
Funding Agency and Grant Number
Corresponding Author	Krevosha Pillay, Department of Surgery, University of Witwatersrand, School of Clinical Medicine, 7 York Road, Johannesburg 2193, Gauteng, South Africa. krevoshap@gmail.com
Key Words	Amoebic liver abscess; Hydatid liver disease; Liver Echinococcosis; Human Immunodeficiency Virus; Pyogenic liver abscess; Percutaneous drainage
Core Tip	The incidence, etiology and microbiology of liver abscesses vary across geographical areas. There is a paucity of published data evaluating the characteristics of liver abscesses and hydatid liver disease in Sub Saharan Africa and other low-and middle-income countries. Human immunodeficiency virus and diabetes mellitus were major co-morbidities noted across all groups, highlighting immunosuppression as an important factor in the pathogenesis of infective liver collections. The microbiology of pyogenic collections is similar to that described in Asian populations, with Klebsiella as the predominant isolate. The majority of patients were managed non-operatively, with surgery reserved for complications. The small number of hydatid disease in this study makes it difficult to draw significant conclusions in this group of patients, and further prospective studies are required.
Citation	<p>Pillay K, Khan ZA, Nweke EE, Omoshoro-Jones J. Clinicopathological presentation of liver abscesses and hydatid liver disease from two South African tertiary hospitals. <i>World J Hepatol</i> 2024; 16(12): 1417-1428</p>

Received	2024-04-17 19:24
Peer-Review Started	2024-04-17 19:24
To Make the First Decision
Return for Revision	2024-09-18 09:02
Revised	2024-10-02 04:19
Second Decision	2024-10-29 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-29 10:12
Articles in Press	2024-10-29 10:12
Publication Fee Transferred	2024-11-05 09:24
Edit the Manuscript by Language Editor	2024-11-18 01:02
Typeset the Manuscript	2024-11-22 00:45

ISSN	1948-5182 (online)
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