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Articles in Press
7/9/2024 6:45:37 AM | Browse: 72 | Download: 8
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Prospective Study |
Article Title |
Impact of oxaliplatin and trastuzumab combination therapy on tumor markers and T lymphocyte subsets for advanced gastric cancer
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Cheng-Wan Zheng, Yun-Mo Yang and Hui Yang |
Funding Agency and Grant Number |
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Corresponding Author |
Hui Yang, MMed, Chief Physician, Department of Thyroid Surgery, The Affiliated Hospital of Southwest Medical University, No. 25 Taiping Street, Luzhou 646000, Sichuan Province, China. yh65011@163.com |
Key Words |
Advanced gastric cancer; Oxaliplatin; Trastuzumab; Serum tumor markers; T lymphocyte subsets; Predictive biomarkers |
Core Tip |
An investigation of the effects of oxaliplatin and trastuzumab combination therapy on serum tumor markers and T lymphocyte subsets in patients with advanced gastric cancer (AGC) revealed significant reductions in carcinoembryonic antigen, cancer antigen 19-9, and cancer antigen 72-4 levels, as well as favorable changes in T cell populations. Patients with significantly decreased tumor marker levels and increased CD4+/CD8+ ratio exhibited better treatment responses. The therapy not only targets tumors but also boosts immune responses in patients with AGC. Serum markers and T cell subsets are potential predictive biomarkers for treatment outcomes in patients with AGC receiving this combined treatment. |
Citation |
<p>Zheng CW, Yang YM, Yang H. Impact of oxaliplatin and trastuzumab combination therapy on tumor markers and T lymphocyte subsets for advanced gastric cancer. <i>World J Gastrointest Oncol</i> 2024; 16(9): 3905-3912</p> |
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Received |
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2024-06-05 11:05 |
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Peer-Review Started |
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2024-06-05 11:05 |
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To Make the First Decision |
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Return for Revision |
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2024-06-25 10:56 |
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Revised |
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2024-07-03 03:59 |
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Second Decision |
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2024-07-09 02:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-07-09 06:45 |
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Articles in Press |
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2024-07-09 06:45 |
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Publication Fee Transferred |
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2024-07-14 16:24 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-07-29 09:21 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
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