Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	97118
Country	China

Category	Oncology
Manuscript Type	Basic Study
Article Title	Impact and mechanism study of dioscin on biological characteristics of colorectal cancer cells
Manuscript Source	Unsolicited Manuscript
All Author List	Xie-Xiao Cai, Zhen-Feng Huang, Fu-Yang Tu and Jie Yu
Funding Agency and Grant Number
Corresponding Author	Jie Yu, BMed, N/A, Department of Gastrointestinal Surgery, The Third Affiliated Hospital of Wenzhou Medical University, No. 108 Wansong Road, Wenzhou 325200, Zhejiang Province, China. 15968760998@163.com
Key Words	Dioscin; Colorectal cancer; Notch1; Cell apoptosis; Cell proliferation
Core Tip	This study investigates the anticancer effects of dioscin on colorectal cancer (CRC) cells (HCT116). Our findings reveal that dioscin inhibits cell viability, promotes apoptosis, and suppresses migration and invasion by modulating the Notch1 signaling pathway. These results highlight the potential of dioscin as a therapeutic agent against CRC.
Citation	Cai XX, Huang ZF, Tu FY, Yu J. Impact and mechanism study of dioscin on biological characteristics of colorectal cancer cells. World J Gastrointest Oncol 2024; In press

Received	2024-08-01 08:13
Peer-Review Started	2024-08-01 08:13
To Make the First Decision
Return for Revision	2024-08-19 10:18
Revised	2024-09-11 09:02
Second Decision	2024-09-29 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-29 08:12
Articles in Press	2024-09-29 08:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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