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Articles in Press
9/29/2024 8:12:36 AM | Browse: 144 | Download: 0
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Impact and mechanism study of dioscin on biological characteristics of colorectal cancer cells
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xie-Xiao Cai, Zhen-Feng Huang, Fu-Yang Tu and Jie Yu |
| Funding Agency and Grant Number |
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| Corresponding Author |
Jie Yu, BMed, N/A, N/A, Department of Gastrointestinal Surgery, The Third Affiliated Hospital of Wenzhou Medical University, No. 108 Wansong Road, Wenzhou 325200, Zhejiang Province, China. 15968760998@163.com |
| Key Words |
Cell proliferation; Cell apoptosis; Notch1; Colorectal cancer; Dioscin |
| Core Tip |
This study investigates the anticancer effects of dioscin on colorectal cancer (CRC) cells (HCT116). Our findings reveal that dioscin inhibits cell viability, promotes apoptosis, and suppresses migration and invasion by modulating the Notch1 signaling pathway. These results highlight the potential of dioscin as a therapeutic agent against CRC. |
| Citation |
Cai XX, Huang ZF, Tu FY, Yu J. Impact and mechanism study of dioscin on biological characteristics of colorectal cancer cells. World J Gastrointest Oncol 2024; 16(11): 4456-4467 |
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Received |
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2024-08-01 08:13 |
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Peer-Review Started |
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2024-08-01 08:13 |
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First Decision by Editorial Office Director |
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2024-08-19 10:18 |
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Return for Revision |
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2024-08-19 10:18 |
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Revised |
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2024-09-11 09:02 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-09-29 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-09-29 08:12 |
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Articles in Press |
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2024-09-29 08:12 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-10-11 12:52 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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