Publication Name	World Journal of Clinical Oncology
Manuscript ID	97823
Country	United States

Category	Oncology
Manuscript Type	Case Report
Article Title	Pembrolizumab-induced Guillain-Barré syndrome in triple-negative breast cancer: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Phani Bhavana Cherukuri, Muhammad Tayyeb, Sai Rakshith Gaddameedi, Doantrang Du and Trishala Meghal
Funding Agency and Grant Number
Corresponding Author	Phani Bhavana Cherukuri, MD, Department of Internal Medicine, Monmouth Medical Center, 300 2nd Avenue, Long Branch, NJ 07740, United States. dr.bhavana.cherukuri22@gmail.com
Key Words	Pembrolizumab; Guillain-Barré syndrome; Triple-negative breast cancer; Immune-related adverse events; Intravenous immunoglobulin therapy; High-dose steroids; Case report
Core Tip	The immune checkpoint inhibitor pembrolizumab can cause rare immune-related adverse events like Guillain-Barré syndrome. This report details a patient with stage IIIB triple-negative breast cancer who developed Guillain-Barré syndrome after pembrolizumab treatment. Initial treatment with intravenous immunoglobulin was insufficient, but a combination of intravenous immunoglobulin and high-dose steroids led to significant improvement. This case highlights the importance of recognizing neurological complications in patients treated with pembrolizumab and emphasizes the need for timely diagnosis and multidisciplinary management of such complications.
Citation	<p>Cherukuri PB, Tayyeb M, Gaddameedi SR, Du D, Meghal T. Pembrolizumab-induced Guillain-Barré syndrome in triple-negative breast cancer: A case report. <i>World J Clin Oncol</i> 2025; 16(2): 97823</p>

Received	2024-06-10 03:51
Peer-Review Started	2024-06-10 03:51
To Make the First Decision
Return for Revision	2024-09-17 02:58
Revised	2024-10-21 01:13
Second Decision	2024-11-08 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-08 08:33
Articles in Press	2024-11-08 08:33
Publication Fee Transferred	2024-10-25 14:55
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-25 10:05

ISSN	2218-4333 (online)
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